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Phosphorylated BMAL1:CLOCK,NPAS2 and coactivators positively regulate expression of Period-1 (PER1) Show undefined attributes

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authored

[InstanceEdit:9909554] May, Bruce, 2024年05月14日

category uncertain

compartment

created [InstanceEdit:9909554] May, Bruce, 2024年05月14日

dbId 9909561

deleted

[Deleted:9938769] Deletion of instance: 549533

displayName Phosphorylated BMAL1:CLOCK,NPAS2 and coactivators positively regulate expression of Period-1 (PER1)

edited

[InstanceEdit:9909554] May, Bruce, 2024年05月14日

eventOf

[Pathway:R-HSA-9931510] Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes - Homo sapiens

followingEvent

[BlackBoxEvent:R-HSA-9909392] Formation of CRY:PER:Kinase complex - Homo sapiens

inferredFrom

[BlackBoxEvent:R-MMU-9909564] Phosphorylated Bmal1:Clock,Npas2 and coactivators positively regulate expression of Period-1 (Per1) - Mus musculus

input

[EntityWithAccessionedSequence:R-HSA-5641209] PER1 gene [nucleoplasm]

isChimeric false

isInDisease false

isInferred true

literatureReference

maxDepth 1

modified [InstanceEdit:9938697] May, Bruce, 2025年02月18日

name

Phosphorylated BMAL1:CLOCK,NPAS2 and coactivators positively regulate expression of Period-1 (PER1)

output

[EntityWithAccessionedSequence:R-HSA-400373] PER1 [cytosol]

precedingEvent

[Reaction:R-HSA-9922982] p-S90-BMAL1:p-T451,T461-CLOCK,p-NPAS2 and coactivators bind the PER1 gene - Homo sapiens

previousReviewStatus [ReviewStatus:9821383] three stars

regulatedBy

regulationReference

releaseDate 2025年03月26日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

schemaClass BlackBoxEvent

species

[Species:48887] Homo sapiens

stId R-HSA-9909561

summation

Referrals

(replacementInstances)

[Deleted:9938769] Deletion of instance: 549533

(precedingEvent)

[BlackBoxEvent:R-HSA-9909392] Formation of CRY:PER:Kinase complex

(hasEvent)

[Pathway:R-HSA-9931510] Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes

(inferredTo)

[BlackBoxEvent:R-MMU-9909564] Phosphorylated Bmal1:Clock,Npas2 and coactivators positively regulate expression of Period-1 (Per1)

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