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Schema
>
Complex
>
Entries
Spliceosomal C* complex [nucleoplasm]
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catalystActivities
[CatalystActivity:9794538] second spliceosomal transesterification activity of Spliceosomal C* complex [nucleoplasm]
compartment
[Compartment:7660] nucleoplasm
consumedByEvent
[BlackBoxEvent:R-HSA-9770236] Formation of the Spliceosomal P complex and exon ligation - Homo sapiens
created
[InstanceEdit:9770146] May, Bruce, 2022年03月24日
dbId
9770118
displayName
Spliceosomal C* complex [nucleoplasm]
hasComponent
[DefinedSet:R-HSA-9769564] Alternative Splicing Factors [nucleoplasm]
[EntityWithAccessionedSequence:R-HSA-156649] ALYREF [nucleoplasm]
[DefinedSet:R-HSA-9770781] ASAP complex, PSAP complex [nucleoplasm]
[EntityWithAccessionedSequence:R-HSA-9769591] CACTIN [nucleoplasm]
[EntityWithAccessionedSequence:R-HSA-9769561] CCDC12 [nucleoplasm]
[EntityWithAccessionedSequence:R-HSA-72062] CDC40 [nucleoplasm]
[Complex:R-HSA-8849113] Core EJC [nucleoplasm]
[EntityWithAccessionedSequence:R-HSA-8865956] CWC22 [nucleoplasm]
[EntityWithAccessionedSequence:R-HSA-8849139] DDX39B [nucleoplasm]
[EntityWithAccessionedSequence:R-HSA-9769601] DDX41 [nucleoplasm]
[EntityWithAccessionedSequence:R-HSA-3900136] DDX5 [nucleoplasm]
[EntityWithAccessionedSequence:R-HSA-5688092] DHX8 [nucleoplasm]
[EntityWithAccessionedSequence:R-HSA-9769598] FAM32A [nucleoplasm]
[EntityWithAccessionedSequence:R-HSA-9769599] FAM50A [nucleoplasm]
[EntityWithAccessionedSequence:R-HSA-72073] hSLU7 [nucleoplasm]
[Complex:R-HSA-9770418] mRNA 5' exon:CBC complex [nucleoplasm]
[Complex:R-HSA-9770422] mRNA intron lariat, 3'exon:RNA Polymerase II [nucleoplasm]
[EntityWithAccessionedSequence:R-HSA-9769592] PPIG [nucleoplasm]
[EntityWithAccessionedSequence:R-HSA-8867892] PPIL1 [nucleoplasm]
[EntityWithAccessionedSequence:R-HSA-9769562] PPIL2 [nucleoplasm]
[EntityWithAccessionedSequence:R-HSA-8952110] PPIL3 [nucleoplasm]
[EntityWithAccessionedSequence:R-HSA-8952113] PPIL4 [nucleoplasm]
[EntityWithAccessionedSequence:R-HSA-8867893] PPWD1 [nucleoplasm]
[EntityWithAccessionedSequence:R-HSA-9769594] PRKRIP1 [nucleoplasm]
[Complex:R-HSA-5420896] PRP19-CDC5L complex [nucleoplasm]
[Complex:R-HSA-9769565] PRP19-CDC5L related complex [nucleoplasm]
[EntityWithAccessionedSequence:R-HSA-5688093] PRPF18 [nucleoplasm]
[EntityWithAccessionedSequence:R-HSA-9769593] SDE2 [nucleoplasm]
[EntityWithAccessionedSequence:R-HSA-6791189] SKIV2L2 [nucleoplasm]
[EntityWithAccessionedSequence:R-HSA-156781] SRRM1 [nucleoplasm]
[EntityWithAccessionedSequence:R-HSA-8865888] SRRM2 [nucleoplasm]
[EntityWithAccessionedSequence:R-HSA-6814858] SRRT [nucleoplasm]
[EntityWithAccessionedSequence:R-HSA-9769596] STEEP1 [nucleoplasm]
[EntityWithAccessionedSequence:R-HSA-8867884] SYF2 [nucleoplasm]
[Complex:R-HSA-8869309] U2 12S snRNP [nucleoplasm]
[Complex:R-HSA-9769567] U5 snRNP (no DDX23,PRPF6,TXNL4A) [nucleoplasm]
[Complex:R-HSA-9794541] U6 snRNA:2Mg2+ [nucleoplasm]
[EntityWithAccessionedSequence:R-HSA-156776] UPF3B [nucleoplasm]
inDisease
false
inferredTo
[Complex:R-MMU-9770118] Spliceosomal C* complex [nucleoplasm] - Mus musculus
[Complex:R-RNO-9770118] Spliceosomal C* complex [nucleoplasm] - Rattus norvegicus
[Complex:R-CFA-9770118] Spliceosomal C* complex [nucleoplasm] - Canis familiaris
[Complex:R-BTA-9770118] Spliceosomal C* complex [nucleoplasm] - Bos taurus
[Complex:R-SSC-9770118] Spliceosomal C* complex [nucleoplasm] - Sus scrofa
[Complex:R-DRE-9770118] Spliceosomal C* complex [nucleoplasm] - Danio rerio
[Complex:R-XTR-9770118] Spliceosomal C* complex [nucleoplasm] - Xenopus tropicalis
[Complex:R-GGA-9770118] Spliceosomal C* complex [nucleoplasm] - Gallus gallus
[Complex:R-DME-9770118] Spliceosomal C* complex [nucleoplasm] - Drosophila melanogaster
[Complex:R-CEL-9770118] Spliceosomal C* complex [nucleoplasm] - Caenorhabditis elegans
[Complex:R-DDI-9770118] Spliceosomal C* complex [nucleoplasm] - Dictyostelium discoideum
[Complex:R-SPO-9770118] Spliceosomal C* complex [nucleoplasm] - Schizosaccharomyces pombe
[Complex:R-PFA-9770118] Spliceosomal C* complex [nucleoplasm] - Plasmodium falciparum
literatureReference
[LiteratureReference:72132] Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis.
[LiteratureReference:9769583] Structural Insights into Nuclear pre-mRNA Splicing in Higher Eukaryotes
[LiteratureReference:5566504] Small nuclear ribonucleoprotein remodeling during catalytic activation of the spliceosome
[LiteratureReference:8865916] Isolation of an active step I spliceosome and composition of its RNP core
[LiteratureReference:9770783] An Atomic Structure of the Human Spliceosome
[LiteratureReference:9770792] Cryo-EM structure of a human spliceosome activated for step 2 of splicing
maxDepth
5
modified
[InstanceEdit:9818132] May, Bruce, 2022年10月12日
name
Spliceosomal C* complex
Spliceosomal Active C complex (update)
producedByEvent
[BlackBoxEvent:R-HSA-9770141] Formation of the Spliceosomal C* complex - Homo sapiens
schemaClass
Complex
species
[Species:48887] Homo sapiens
stId
R-HSA-9770118
Referrals
(input)
[BlackBoxEvent:R-HSA-9770236] Formation of the Spliceosomal P complex and exon ligation
(output)
[BlackBoxEvent:R-HSA-9770141] Formation of the Spliceosomal C* complex
(physicalEntity)
[CatalystActivity:9794538] second spliceosomal transesterification activity of Spliceosomal C* complex [nucleoplasm]
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