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Factor I inactivates plasma Factor H-bound C3b Show undefined attributes

authored

[InstanceEdit:981647] Jupe, S, 2010年10月26日

catalystActivity

[CatalystActivity:977368] serine-type endopeptidase activity of CFI:CFH:C3b [extracellular region]

category transition

compartment

[Compartment:984] extracellular region

created [InstanceEdit:976791] Jupe, S, 2010年10月13日

dbId 976743

displayName Factor I inactivates plasma Factor H-bound C3b

edited

[InstanceEdit:983442] Jupe, S, 2010年11月01日

eventOf

[Pathway:R-HSA-977606] Regulation of Complement cascade - Homo sapiens

input

[Complex:R-HSA-976770] CFI:CFH:C3b [extracellular region]

isChimeric false

isInDisease false

isInferred false

literatureReference

[LiteratureReference:976744] Kinetic and thermodynamic analysis of the control of C3b by the complement regulatory proteins factors H and I

maxDepth 1

modified [InstanceEdit:10680101] Weiser, Joel, 2025年08月27日

name

Factor I inactivates plasma Factor H-bound C3b

orthologousEvent

output

precedingEvent

[Reaction:R-HSA-976810] Complement factor I binds to extracellular Factor H:C3b - Homo sapiens

releaseDate 2012年03月13日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-976743

summation

[Summation:976792] Complement factor I (CFI) cleaves the alpha chain of C3b at ...

updateTrackers

[UpdateTracker:9783540] Update Tracker - [Reaction:976743] Factor I inactivates plasma Factor H-bound C3b - v56:[modifyText]

Referrals

(updatedInstance)

[UpdateTracker:9783540] Update Tracker - [Reaction:976743] Factor I inactivates plasma Factor H-bound C3b - v56:[modifyText]

(hasEvent)

[Pathway:R-HSA-977606] Regulation of Complement cascade

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