Reactome Pathway Database

Schema > Reaction > Entries

SARS-CoV-1 3a tetramerizes Show undefined attributes

authored

[InstanceEdit:9731032] Stephan, Ralf, 2021年05月07日

category binding

compartment

[Compartment:876] plasma membrane

created [InstanceEdit:9731037] Stephan, Ralf, 2021年05月12日

crossReference

[DatabaseIdentifier:11944911] Mondo:0005091

dbId 9731012

disease

[Disease:9678120] severe acute respiratory syndrome

displayName SARS-CoV-1 3a tetramerizes

edited

[InstanceEdit:9815358] Stephan, Ralf, 2022年08月17日

eventOf

[Pathway:R-HSA-9692916] SARS-CoV-1 activates/modulates innate immune responses - Homo sapiens

followingEvent

[Reaction:R-HSA-9731072] SARS-CoV-1 3a tetramer induces potassium efflux - Homo sapiens

input

4 × [EntityWithAccessionedSequence:R-COV-9685962] O-glycosyl 3a [plasma membrane]

isChimeric false

isInDisease true

isInferred false

literatureReference

maxDepth 1

modified [InstanceEdit:9830342] Matthews, Lisa, 2023年03月08日

name

SARS-CoV-1 3a tetramerizes

output

[Complex:R-COV-9685937] O-glycosyl 3a tetramer [plasma membrane]

regulatedBy

[PositiveRegulation:9731020] Positive regulation by 'RIPK3:O-glycosyl 3a [plasma membrane]'

regulationReference

[RegulationReference:9731062] Positive regulation by 'RIPK3:O-glycosyl 3a [plasma membrane]' SARS-Coronavirus Open Reading Frame-3a drives multimodal necrotic cell death

relatedSpecies

[Species:9678119] Human SARS coronavirus

releaseDate 2022年09月14日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

[InstanceEdit:9713569] D'Eustachio, Peter, 2021年01月26日

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-9731012

summation

[Summation:9731015] SARS-CoV-1 viroporin 3a is a membrane-bound protein that tra...

Referrals

(precedingEvent)

[Reaction:R-HSA-9731072] SARS-CoV-1 3a tetramer induces potassium efflux

(hasEvent)

[Pathway:R-HSA-9692916] SARS-CoV-1 activates/modulates innate immune responses

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