Reactome Pathway Database

Schema > EntityWithAccessionedSequence > Entries

TP53 R342P [nucleoplasm] Show undefined attributes

compartment

[Compartment:7660] nucleoplasm

created [InstanceEdit:9726100] Orlic-Milacic, Marija, 2021年04月05日

crossReference

dbId 9726101

disease

displayName TP53 R342P [nucleoplasm]

endCoordinate 393

hasModifiedResidue

[ReplacedResidue:9726105] L-arginine 342 replaced with L-proline

inDisease true

literatureReference

[LiteratureReference:9726103] p53 mutants without a functional tetramerisation domain are not oncogenic
[LiteratureReference:9726293] Characterization of p53 mutants identified in human tumors with a missense mutation in the tetramerization domain
[LiteratureReference:9726313] Cancer-associated p53 tetramerization domain mutants: quantitative analysis reveals a low threshold for tumor suppressor inactivation

maxDepth 1

memberOf

[CandidateSet:R-HSA-9720037] TP53 mutants (tetramerization) [nucleoplasm] - Homo sapiens

modified [InstanceEdit:9730928] Matthews, Lisa, 2021年05月12日

name

TP53 R342P

referenceEntity [ReferenceGeneProduct:uniprot:P04637] UniProt:P04637 TP53

referenceType ReferenceGeneProduct

schemaClass EntityWithAccessionedSequence

species [Species:48887] Homo sapiens

stId R-HSA-9726101

startCoordinate 1

Referrals

(hasMember)

[CandidateSet:R-HSA-9720037] TP53 mutants (tetramerization) [nucleoplasm]

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