Reactome Pathway Database

Schema > EntityWithAccessionedSequence > Entries

FLT3 A848P [plasma membrane] Show undefined attributes

compartment

[Compartment:876] plasma membrane

componentOf

created [InstanceEdit:9702907] Rothfels, Karen, 2020年10月02日

crossReference

dbId 9702909

disease

displayName FLT3 A848P [plasma membrane]

endCoordinate 993

hasModifiedResidue

[ReplacedResidue:9702908] L-alanine 848 replaced with L-proline

inDisease true

literatureReference

[LiteratureReference:9699384] The secondary FLT3-ITD F691L mutation induces resistance to AC220 in FLT3-ITD+ AML but retains in vitro sensitivity to PKC412 and Sunitinib
[LiteratureReference:9702875] Identification of a secondary FLT3/A848P mutation in a patient with FLT3-ITD-positive blast phase CMML and response to sunitinib and sorafenib

maxDepth 1

memberOf

name

FLT3 A848P

referenceEntity [ReferenceGeneProduct:uniprot:P36888] UniProt:P36888 FLT3

referenceType ReferenceGeneProduct

schemaClass EntityWithAccessionedSequence

species [Species:48887] Homo sapiens

stId R-HSA-9702909

startCoordinate 27

Referrals

(hasMember)

(hasComponent)

[Complex:R-HSA-9702911] FLT3 A848P dimer [plasma membrane]

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