Reactome Pathway Database

Schema > BlackBoxEvent > Entries

CD274 gene expression downstream of ALK signaling Show undefined attributes

authored

[InstanceEdit:9725664] Rothfels, Karen, 2021年03月30日

category omitted

compartment

[Compartment:7660] nucleoplasm

created [InstanceEdit:9701563] Rothfels, Karen, 2020年09月26日

dbId 9701562

displayName CD274 gene expression downstream of ALK signaling

edited

[InstanceEdit:9725664] Rothfels, Karen, 2021年03月30日

eventOf

[Pathway:R-HSA-9701898] STAT3 nuclear events downstream of ALK signaling - Homo sapiens

input

[EntityWithAccessionedSequence:R-HSA-9701419] CD274 gene [nucleoplasm]

isChimeric false

isInDisease false

isInferred false

literatureReference

maxDepth 1

modified [InstanceEdit:9830342] Matthews, Lisa, 2023年03月08日

name

CD274 gene expression downstream of ALK signaling

output

[EntityWithAccessionedSequence:R-HSA-3211776] CD274 [plasma membrane]

precedingEvent

[Reaction:R-HSA-9701537] p-Y705, S727 STAT3 dimer binds CD274 gene - Homo sapiens

regulatedBy

[PositiveGeneExpressionRegulation:9701542] Positive gene expression regulation by 'p-Y705, S727 STAT3 dimer:CD274 gene [nucleoplasm]'

releaseDate 2021年06月09日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

[InstanceEdit:9729891] Inghirami, Giorgio, 2021年05月04日

schemaClass BlackBoxEvent

species

[Species:48887] Homo sapiens

stId R-HSA-9701562

summation

[Summation:9701495] ALK signaling promotes expression of the CD274 gene by stimu...

Referrals

(hasEvent)

[Pathway:R-HSA-9701898] STAT3 nuclear events downstream of ALK signaling

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