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SARS-CoV-1 3a binds TRAF3 within NLRP3 inflammasome Show undefined attributes

authored

[InstanceEdit:9692648] Shamovsky, Veronica, 2020年06月25日

category binding

compartment

created [InstanceEdit:9685275] Shamovsky, Veronica, 2020年04月23日

crossReference

[DatabaseIdentifier:11944911] Mondo:0005091

dbId 9685281

disease

[Disease:9678120] severe acute respiratory syndrome

displayName SARS-CoV-1 3a binds TRAF3 within NLRP3 inflammasome

edited

[InstanceEdit:9796665] Shamovsky, Veronica, 2022年08月11日

eventOf

[Pathway:R-HSA-9692916] SARS-CoV-1 activates/modulates innate immune responses - Homo sapiens

input

isChimeric false

isInDisease true

isInferred false

literatureReference

[LiteratureReference:9685267] Severe acute respiratory syndrome coronavirus ORF3a protein activates the NLRP3 inflammasome by promoting TRAF3-dependent ubiquitination of ASC

maxDepth 1

modified [InstanceEdit:9830342] Matthews, Lisa, 2023年03月08日

name

SARS-CoV-1 3a binds TRAF3 within NLRP3 inflammasome

output

[Complex:R-HSA-9685242] 3a:NLRP3 oligomer:MAVS:TRAF3:PYCARD [mitochondrial outer membrane]

relatedSpecies

[Species:9678119] Human SARS coronavirus

releaseDate 2022年09月14日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

[InstanceEdit:9713569] D'Eustachio, Peter, 2021年01月26日

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-9685281

summation

[Summation:9685262] Severe acute respiratory syndrome coronavirus type 1 (SARS?C...

Referrals

(hasEvent)

[Pathway:R-HSA-9692916] SARS-CoV-1 activates/modulates innate immune responses

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