Reactome Pathway Database

Schema > BlackBoxEvent > Entries

SARS-CoV-1 9b recruits ITCH to MAVS Show undefined attributes

authored

[InstanceEdit:9692648] Shamovsky, Veronica, 2020年06月25日

catalystActivity

[CatalystActivity:990525] ubiquitin protein ligase activity of ITCH [cytosol]

category omitted

compartment

created [InstanceEdit:9685194] Shamovsky, Veronica, 2020年04月23日

crossReference

[DatabaseIdentifier:11944911] Mondo:0005091

dbId 9685195

disease

[Disease:9678120] severe acute respiratory syndrome

displayName SARS-CoV-1 9b recruits ITCH to MAVS

edited

[InstanceEdit:9796665] Shamovsky, Veronica, 2022年08月11日

eventOf

[Pathway:R-HSA-9692916] SARS-CoV-1 activates/modulates innate immune responses - Homo sapiens

input

isChimeric false

isInDisease true

isInferred false

literatureReference

[LiteratureReference:9685176] SARS-coronavirus open reading frame-9b suppresses innate immunity by targeting mitochondria and the MAVS/TRAF3/TRAF6 signalosome

maxDepth 1

modified [InstanceEdit:9830342] Matthews, Lisa, 2023年03月08日

name

SARS-CoV-1 9b recruits ITCH to MAVS

output

[Complex:R-HSA-9685173] 9b:K48polyUb-MAVS:PCBP2:ITCH [mitochondrial outer membrane]

precedingEvent

[Reaction:R-HSA-9685189] SARS-CoV-1 9b binds MAVS and PCBP2 - Homo sapiens

relatedSpecies

[Species:9678119] Human SARS coronavirus

releaseDate 2022年09月14日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

[InstanceEdit:9713569] D'Eustachio, Peter, 2021年01月26日

schemaClass BlackBoxEvent

species

[Species:48887] Homo sapiens

stId R-HSA-9685195

summation

[Summation:9685183] On viral infection poly(rC) binding protein 2 (PCBP2) binds ...

Referrals

(hasEvent)

[Pathway:R-HSA-9692916] SARS-CoV-1 activates/modulates innate immune responses

© 2025 Reactome

Cite Us!