Reactome Pathway Database

Schema > CandidateSet > Entries

ripretinib-sensitive KIT mutants [plasma membrane] Show undefined attributes

compartment

[Compartment:876] plasma membrane

componentOf

[Complex:R-HSA-9681383] ripretinib-sensitive KIT:ripretinib [plasma membrane] - Homo sapiens

consumedByEvent

[Reaction:R-HSA-9681382] KIT mutants bind ripretinib - Homo sapiens

created [InstanceEdit:9681381] Rothfels, Karen, 2020年04月01日

crossReference

[DatabaseIdentifier:11944892] Mondo:0004992

dbId 9681384

disease

[Disease:1500689] cancer

displayName ripretinib-sensitive KIT mutants [plasma membrane]

hasCandidate

hasMember

inDisease true

literatureReference

[LiteratureReference:9674274] Ripretinib (DCC-2618) Is a Switch Control Kinase Inhibitor of a Broad Spectrum of Oncogenic and Drug-Resistant KIT and PDGFRA Variants

maxDepth 2

name

ripretinib-sensitive KIT mutants

schemaClass CandidateSet

species

[Species:48887] Homo sapiens

stId R-HSA-9681384

Referrals

(hasComponent)

[Complex:R-HSA-9681383] ripretinib-sensitive KIT:ripretinib [plasma membrane]

(input)

[Reaction:R-HSA-9681382] KIT mutants bind ripretinib

(diseaseEntity)

[EntityFunctionalStatus:9686617] gain_of_function of ripretinib-sensitive KIT mutants [plasma membrane]

© 2025 Reactome

Cite Us!