Reactome Pathway Database

Schema > Complex > Entries

p-6Y-ERBB2 R678Q:EGF:p-6Y-EGFR [plasma membrane] Show undefined attributes

compartment

[Compartment:876] plasma membrane

componentOf

[Complex:R-HSA-9665924] p-6Y-ERBB2 R678Q:EGF:p-6Y-EGFR:PLCG1 [plasma membrane] - Homo sapiens

consumedByEvent

[Reaction:R-HSA-9665706] Phosphorylated heterodimers of ERBB2 TMD/JMD mutants and EGFR bind PLCG1 - Homo sapiens

created [InstanceEdit:9665927] Orlic-Milacic, Marija, 2019年11月01日

crossReference

[DatabaseIdentifier:11944892] Mondo:0004992

dbId 9665925

disease

[Disease:1500689] cancer

displayName p-6Y-ERBB2 R678Q:EGF:p-6Y-EGFR [plasma membrane]

hasComponent

inDisease true

includedLocation

[Compartment:984] extracellular region

isChimeric false

maxDepth 3

name

p-6Y-ERBB2 R678Q:EGF:p-6Y-EGFR

producedByEvent

[Reaction:R-HSA-9665704] Phosphorylated heterodimers of ERBB2 TMD/JMD mutants and EGFR phosphorylate PLCG1 - Homo sapiens

schemaClass Complex

species

[Species:48887] Homo sapiens

stId R-HSA-9665925

Referrals

(output)

[Reaction:R-HSA-9665704] Phosphorylated heterodimers of ERBB2 TMD/JMD mutants and EGFR phosphorylate PLCG1

(hasComponent)

[Complex:R-HSA-9665924] p-6Y-ERBB2 R678Q:EGF:p-6Y-EGFR:PLCG1 [plasma membrane]

(input)

[Reaction:R-HSA-9665706] Phosphorylated heterodimers of ERBB2 TMD/JMD mutants and EGFR bind PLCG1

(diseaseEntity)

[EntityFunctionalStatus:9665923] gain_of_function of p-6Y-ERBB2 R678Q:EGF:p-6Y-EGFR [plasma membrane]

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