Reactome Pathway Database

Schema > EntityWithAccessionedSequence > Entries

BRAF G469E [cytosol] Show undefined attributes

candidateOf

[CandidateSet:R-HSA-6802641] moderate kinase activity BRAF mutants [cytosol] - Homo sapiens

compartment

[Compartment:70101] cytosol

created [InstanceEdit:9648616] Rothfels, Karen, 2019年06月07日

crossReference

dbId 9648618

disease

displayName BRAF G469E [cytosol]

endCoordinate 766

hasModifiedResidue

inDisease true

literatureReference

[LiteratureReference:5672469] Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF
[LiteratureReference:9646947] Beyond BRAF(V600): clinical mutation panel testing by next-generation sequencing in advanced melanoma
[LiteratureReference:5672236] Mutations of the BRAF gene in human cancer
[LiteratureReference:9651037] Germline KRAS and BRAF mutations in cardio-facio-cutaneous syndrome
[LiteratureReference:9651055] Mutation and phenotypic spectrum in patients with cardio-facio-cutaneous and Costello syndrome

maxDepth 1

modified [InstanceEdit:9651201] Rothfels, Karen, 2019年06月25日

name

BRAF G469E
B-RAF

referenceEntity [ReferenceGeneProduct:uniprot:P15056] UniProt:P15056 BRAF

referenceType ReferenceGeneProduct

schemaClass EntityWithAccessionedSequence

species [Species:48887] Homo sapiens

stId R-HSA-9648618

startCoordinate 2

Referrals

(hasCandidate)

[CandidateSet:R-HSA-6802641] moderate kinase activity BRAF mutants [cytosol]

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