Reactome Pathway Database
Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Reactome Pathway Database
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
Schema
>
BlackBoxEvent
>
Entries
Dissociation of phosphorylated MAP2Ks and MAPKs
Show undefined attributes
Go to Details
authored
[InstanceEdit:9610162] Rothfels, Karen, 2018年06月05日
category
omitted
compartment
[Compartment:70101] cytosol
[Compartment:74700] endosome membrane
created
[InstanceEdit:9610162] Rothfels, Karen, 2018年06月05日
dbId
9610154
displayName
Dissociation of phosphorylated MAP2Ks and MAPKs
eventOf
[Pathway:R-HSA-170968] Frs2-mediated activation - Homo sapiens
followingEvent
[Reaction:R-HSA-5674385] p-T,Y MAPKs dimerize - Homo sapiens
input
[Complex:R-HSA-9610140] RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:p-T,Y MAPK complex [endosome membrane]
isChimeric
false
isInDisease
false
isInferred
false
literatureReference
[LiteratureReference:9610074] Co-regulation of the mitogen-activated protein kinase, extracellular signal-regulated kinase 1, and the 90-kDa ribosomal S6 kinase in PC12 cells. Distinct effects of the neurotrophic factor, nerve growth factor, and the mitogenic factor, epidermal growth factor
[LiteratureReference:9610087] Signaling pathways for PC12 cell differentiation: making the right connections
[LiteratureReference:9610094] Transcription factors and effectors that regulate neuronal morphology
maxDepth
1
modified
[InstanceEdit:10867632] Weiser, Joel, 2025年08月27日
name
Dissociation of phosphorylated MAP2Ks and MAPKs
orthologousEvent
[BlackBoxEvent:R-CEL-9610154] Dissociation of phosphorylated MAP2Ks and MAPKs - Caenorhabditis elegans
[BlackBoxEvent:R-DME-9610154] Dissociation of phosphorylated MAP2Ks and MAPKs - Drosophila melanogaster
[BlackBoxEvent:R-GGA-9610154] Dissociation of phosphorylated MAP2Ks and MAPKs - Gallus gallus
[BlackBoxEvent:R-SSC-9610154] Dissociation of phosphorylated MAP2Ks and MAPKs - Sus scrofa
[BlackBoxEvent:R-BTA-9610154] Dissociation of phosphorylated MAP2Ks and MAPKs - Bos taurus
[BlackBoxEvent:R-RNO-9610154] Dissociation of phosphorylated MAP2Ks and MAPKs - Rattus norvegicus
[BlackBoxEvent:R-MMU-9610154] Dissociation of phosphorylated MAP2Ks and MAPKs - Mus musculus
output
[DefinedSet:R-HSA-5672721] p-2S MAP2K homo/heterodimers [cytosol]
[DefinedSet:R-HSA-169289] p-T,Y MAPKs [cytosol]
[Complex:R-HSA-9610130] RAP1:GTP:activated BRAF dimer [endosome membrane]
precedingEvent
[Reaction:R-HSA-9610156] MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF - Homo sapiens
releaseDate
2019年09月10日
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:9658256] D'Eustachio, Peter, 2019年08月12日
schemaClass
BlackBoxEvent
species
[Species:48887] Homo sapiens
stId
R-HSA-9610154
summation
[Summation:9610164] The mechanisms governing dissocation of activated signaling ...
Referrals
(hasEvent)
[Pathway:R-HSA-170968] Frs2-mediated activation
(precedingEvent)
[Reaction:R-HSA-5674385] p-T,Y MAPKs dimerize
[NegativePrecedingEvent:9865769] Futile Cycle: Dissociation of phosphorylated MAP2Ks and MAPKs
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
Download
Close
AltStyle
によって変換されたページ
(->オリジナル)
/
アドレス:
モード:
デフォルト
音声ブラウザ
ルビ付き
配色反転
文字拡大
モバイル