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GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol
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authored
[InstanceEdit:113845] D'Eustachio, P, 2004年06月23日 11:10:00
catalystActivity
[CatalystActivity:8981550] D-glucose transmembrane transporter activity of GLUT4 / SLC2A4 tetramer [plasma membrane]
category
transition
compartment
[Compartment:70101] cytosol
[Compartment:876] plasma membrane
[Compartment:984] extracellular region
created
[InstanceEdit:8981563] D'Eustachio, Peter, 2017年03月10日
dbId
8981570
displayName
GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol
edited
[InstanceEdit:113845] D'Eustachio, P, 2004年06月23日 11:10:00
eventOf
[Pathway:R-HSA-189200] Cellular hexose transport - Homo sapiens
goBiologicalProcess
[GO_BiologicalProcess:6808140] D-glucose transmembrane transport
input
[SimpleEntity:R-ALL-70115] Glc [extracellular region]
isInDisease
false
isInferred
false
literatureReference
[LiteratureReference:70143] Regulated transport of the glucose transporter GLUT4
[LiteratureReference:428777] Molecular scanning of insulin-responsive glucose transporter (GLUT4) gene in NIDDM subjects
[LiteratureReference:70388] Cloning and characterization of the major insulin-responsive glucose transporter expressed in human skeletal muscle and other insulin-responsive tissues.
[LiteratureReference:428811] Analysis of the gene sequences of the insulin receptor and the insulin-sensitive glucose transporter (GLUT-4) in patients with common-type non-insulin-dependent diabetes mellitus
maxDepth
1
modified
[InstanceEdit:11064438] Weiser, Joel, 2025年08月28日
name
GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol
negativePrecedingEvent
[NegativePrecedingEvent:9963441] Futile Cycle: GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region
[NegativePrecedingEvent:9963445] Futile Cycle: SLC50A1 transports Glc from cytosol to extracellular region
orthologousEvent
[Reaction:R-PFA-8981570] GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol - Plasmodium falciparum
[Reaction:R-SCE-8981570] GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol - Saccharomyces cerevisiae
[Reaction:R-DDI-8981570] GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol - Dictyostelium discoideum
[Reaction:R-CEL-8981570] GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol - Caenorhabditis elegans
[Reaction:R-DME-8981570] GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol - Drosophila melanogaster
[Reaction:R-GGA-8981570] GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol - Gallus gallus
[Reaction:R-XTR-8981570] GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol - Xenopus tropicalis
[Reaction:R-SSC-8981570] GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol - Sus scrofa
[Reaction:R-BTA-8981570] GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol - Bos taurus
[Reaction:R-CFA-8981570] GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol - Canis familiaris
[Reaction:R-RNO-8981570] GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol - Rattus norvegicus
[Reaction:R-MMU-8981570] GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol - Mus musculus
output
[SimpleEntity:R-ALL-70113] Glc [cytosol]
releaseDate
2004年07月06日
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:433651] He, L, 2009年08月24日
revised
[InstanceEdit:450087] D'Eustachio, P, 2009年12月11日
schemaClass
Reaction
species
[Species:48887] Homo sapiens
stId
R-HSA-8981570
summation
[Summation:8981559] Tetrameric GLUT4, the SLC2A4 gene product, associated with t...
Referrals
(hasEvent)
[Pathway:R-HSA-189200] Cellular hexose transport
(precedingEvent)
[NegativePrecedingEvent:9963464] Futile Cycle: GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol
[NegativePrecedingEvent:9963437] Futile Cycle: GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol
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