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Reaction
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Entries
Association of procollagen type I
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authored
[InstanceEdit:2192896] Jupe, S, 2012年04月11日
category
binding
compartment
[Compartment:17957] endoplasmic reticulum lumen
created
[InstanceEdit:8944228] Jupe, Steve, 2016年11月03日
dbId
8944214
displayName
Association of procollagen type I
edited
[InstanceEdit:8944470] Jupe, Steve, 2016年11月03日
eventOf
[Pathway:R-HSA-8948216] Collagen chain trimerization - Homo sapiens
followingEvent
[Reaction:R-HSA-2022073] Procollagen triple helix formation - Homo sapiens
input
2 ×
[DefinedSet:R-HSA-2025670] Alpha-1(I) propeptides [endoplasmic reticulum lumen]
[DefinedSet:R-HSA-2029425] Alpha-2(I) propeptides [endoplasmic reticulum lumen]
isChimeric
false
isInDisease
false
isInferred
false
literatureReference
[LiteratureReference:2008097] Interchain disulfide bonds in procollagen are located in a large nontriple-helical COOH-terminal domain
[LiteratureReference:2008075] The role of cis-trans isomerization of peptide bonds in the coil leads to and comes from triple helix conversion of collagen
maxDepth
1
modified
[InstanceEdit:10867632] Weiser, Joel, 2025年08月27日
name
Association of procollagen type I
orthologousEvent
[Reaction:R-CEL-8944214] Association of procollagen type I - Caenorhabditis elegans
[Reaction:R-GGA-8944214] Association of procollagen type I - Gallus gallus
[Reaction:R-XTR-8944214] Association of procollagen type I - Xenopus tropicalis
[Reaction:R-DRE-8944214] Association of procollagen type I - Danio rerio
[Reaction:R-SSC-8944214] Association of procollagen type I - Sus scrofa
[Reaction:R-BTA-8944214] Association of procollagen type I - Bos taurus
[Reaction:R-CFA-8944214] Association of procollagen type I - Canis familiaris
[Reaction:R-RNO-8944214] Association of procollagen type I - Rattus norvegicus
[Reaction:R-MMU-8944214] Association of procollagen type I - Mus musculus
output
[Complex:R-HSA-2025669] C-linked procollagen type I trimer [endoplasmic reticulum lumen]
precedingEvent
[BlackBoxEvent:R-HSA-8948231] COLGALT1,COLGALT2:Galactosyl-hydroxylysyl collagen propeptides dissociates - Homo sapiens
[BlackBoxEvent:R-HSA-8948232] Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases - Homo sapiens
[BlackBoxEvent:R-HSA-8948234] P4HB:4-Hyp collagen propeptides dissociates - Homo sapiens
[BlackBoxEvent:R-HSA-8948222] PLOD3:Fe2+ dimer:Galactosyl-hydroxylysyl collagen propeptides dissociates - Homo sapiens
[BlackBoxEvent:R-HSA-8948224] PLOD3:Fe2+ dimer:Glucosyl-galactosyl-hydroxylysyl collagen propeptides dissociates - Homo sapiens
[BlackBoxEvent:R-HSA-8948226] Prolyl 3-hydroxylases:Fe2+:3,4-Hyp collagen propeptides dissociates - Homo sapiens
[BlackBoxEvent:R-HSA-9733216] COL1A2 gene expression is stimulated by p-2S-SMAD3:p-2S-SMAD3:SMAD4 - Homo sapiens
releaseDate
2016年12月12日
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:2267224] Canty-Laird, EG, 2012年05月24日
schemaClass
Reaction
species
[Species:48887] Homo sapiens
stId
R-HSA-8944214
summation
[Summation:2002435] The C-propeptides are essential for the association of three...
Referrals
(hasEvent)
[Pathway:R-HSA-8948216] Collagen chain trimerization
(precedingEvent)
[Reaction:R-HSA-2022073] Procollagen triple helix formation
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