Reactome Pathway Database

Schema > EntityWithAccessionedSequence > Entries

p-BRAF F595L [plasma membrane] Show undefined attributes

compartment

[Compartment:876] plasma membrane

created [InstanceEdit:8936642] Rothfels, Karen, 2016年08月22日

crossReference

dbId 8936641

disease

displayName p-BRAF F595L [plasma membrane]

endCoordinate 766

hasModifiedResidue

inDisease true

literatureReference

[LiteratureReference:5672236] Mutations of the BRAF gene in human cancer
[LiteratureReference:5672469] Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF
[LiteratureReference:9651008] Germline BRAF mutations in Noonan, LEOPARD, and cardiofaciocutaneous syndromes: molecular diversity and associated phenotypic spectrum
[LiteratureReference:9651044] Germline mutations in genes within the MAPK pathway cause cardio-facio-cutaneous syndrome

maxDepth 1

memberOf

[CandidateSet:R-HSA-8936658] phosphorylated moderate kinase activity BRAF mutants [plasma membrane] - Homo sapiens

modified [InstanceEdit:9651203] Rothfels, Karen, 2019年06月25日

name

p-BRAF F595L
B-RAF

referenceEntity [ReferenceGeneProduct:uniprot:P15056] UniProt:P15056 BRAF

referenceType ReferenceGeneProduct

schemaClass EntityWithAccessionedSequence

species [Species:48887] Homo sapiens

stId R-HSA-8936641

startCoordinate 2

updateTrackers

[UpdateTracker:9900626] Update Tracker - [EntityWithAccessionedSequence:8936641] p-BRAF F595L [plasma membrane] - v70:[addDisease, addLiteratureReference, modifyName]

Referrals

(updatedInstance)

[UpdateTracker:9900626] Update Tracker - [EntityWithAccessionedSequence:8936641] p-BRAF F595L [plasma membrane] - v70:[addDisease, addLiteratureReference, modifyName]

(hasMember)

[CandidateSet:R-HSA-8936658] phosphorylated moderate kinase activity BRAF mutants [plasma membrane]

© 2025 Reactome

Cite Us!