Reactome Pathway Database

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RAB5 and GAPVD1 bind AP-2 Show undefined attributes

authored

[InstanceEdit:8871191] Rothfels, Karen, 2016年05月13日

category binding

compartment

[Compartment:24339] clathrin-coated endocytic vesicle membrane

created [InstanceEdit:8871192] Rothfels, Karen, 2016年05月13日

dbId 8871194

displayName RAB5 and GAPVD1 bind AP-2

edited

[InstanceEdit:8871191] Rothfels, Karen, 2016年05月13日

eventOf

[Pathway:R-HSA-8856828] Clathrin-mediated endocytosis - Homo sapiens

followingEvent

[BlackBoxEvent:R-HSA-8871193] Dissociation of AAK1 and dephosphorylation of AP-2 mu2 - Homo sapiens

input

isChimeric false

isInDisease false

isInferred false

literatureReference

maxDepth 1

modified [InstanceEdit:10867632] Weiser, Joel, 2025年08月27日

name

RAB5 and GAPVD1 bind AP-2

orthologousEvent

output

[Complex:R-HSA-8871149] PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane]

precedingEvent

[Reaction:R-HSA-8868658] HSPA8-mediated ATP hydrolysis promotes vesicle uncoating - Homo sapiens

releaseDate 2016年06月15日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

[InstanceEdit:8870617] Antonescu, Costin N, 2016年05月10日

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-8871194

summation

[Summation:8871183] RAB5 is a small GTPase that is implicated in clathrin-mediat...

Referrals

(hasEvent)

[Pathway:R-HSA-8856828] Clathrin-mediated endocytosis

(precedingEvent)

[BlackBoxEvent:R-HSA-8871193] Dissociation of AAK1 and dephosphorylation of AP-2 mu2

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