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Membrane proteases cleave Profilaggrin producing Filaggrin Show undefined attributes

authored

[InstanceEdit:8863769] Jupe, Steve, 2016年03月10日

catalystActivity

[CatalystActivity:8849786] endopeptidase activity of Membrane profilaggrin processing proteases [plasma membrane]

category transition

compartment

created [InstanceEdit:8849810] Jupe, Steve, 2015年12月17日

dbId 8849797

displayName Membrane proteases cleave Profilaggrin producing Filaggrin

edited

[InstanceEdit:8934545] Jupe, Steve, 2016年08月10日

eventOf

[Pathway:R-HSA-6809371] Formation of the cornified envelope - Homo sapiens

followingEvent

[Reaction:R-HSA-8942224] Filaggrin binds Keratin tonofilament:Desmosome - Homo sapiens

input

[EntityWithAccessionedSequence:R-HSA-8849818] FLG(1-4061) [cytosol]

isChimeric false

isInDisease false

isInferred false

literatureReference

maxDepth 1

modified [InstanceEdit:10201029] Weiser, Joel, 2025年08月27日

name

Membrane proteases cleave Profilaggrin producing Filaggrin

orthologousEvent

[Reaction:R-CFA-8849797] Membrane proteases cleave Profilaggrin producing Filaggrin - Canis familiaris

output

[EntityWithAccessionedSequence:R-HSA-6810859] FLG(?-?) [cytosol]

releaseDate 2016年09月19日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

[InstanceEdit:8934809] Blumenberg, Miroslav, 2016年08月12日

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-8849797

summation

[Summation:8849790] Filaggrin is initially synthesized as a large, insoluble, hi...

Referrals

(precedingEvent)

[Reaction:R-HSA-8942224] Filaggrin binds Keratin tonofilament:Desmosome

(hasEvent)

[Pathway:R-HSA-6809371] Formation of the cornified envelope

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