Reactome Pathway Database

Schema > Reaction > Entries

PTK6 phosphorylates PXN Show undefined attributes

authored

[InstanceEdit:8850988] Orlic-Milacic, Marija, 2016年01月04日

catalystActivity

[CatalystActivity:8848605] protein tyrosine kinase activity of p-Y342-PTK6:PXN [cytosol]

category transition

compartment

[Compartment:70101] cytosol

created [InstanceEdit:8848603] Orlic-Milacic, Marija, 2015年12月09日

dbId 8848606

displayName PTK6 phosphorylates PXN

edited

[InstanceEdit:8850988] Orlic-Milacic, Marija, 2016年01月04日

eventOf

[Pathway:R-HSA-8849471] PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases - Homo sapiens

followingEvent

[Reaction:R-HSA-8848611] Phosphorylated PXN recruits the CRK complex - Homo sapiens

input

isChimeric false

isInDisease false

isInferred false

literatureReference

[LiteratureReference:8848601] Brk activates rac1 and promotes cell migration and invasion by phosphorylating paxillin

maxDepth 1

modified [InstanceEdit:10541496] Weiser, Joel, 2025年08月27日

name

PTK6 phosphorylates PXN

orthologousEvent

output

precedingEvent

[Reaction:R-HSA-8848596] PTK6 binds PXN - Homo sapiens

releaseDate 2016年03月23日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

[InstanceEdit:8856649] Pires, Isabel M, 2016年02月07日

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-8848606

summation

[Summation:8848604] Activated PTK6 (BRK) phosphorylates PXN (paxillin) on tyrosi...

Referrals

(hasEvent)

[Pathway:R-HSA-8849471] PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases

(precedingEvent)

[Reaction:R-HSA-8848611] Phosphorylated PXN recruits the CRK complex

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