Reactome Pathway Database

Schema > Reaction > Entries

PTK6 binds PXN Show undefined attributes

authored

[InstanceEdit:8850988] Orlic-Milacic, Marija, 2016年01月04日

category binding

compartment

[Compartment:70101] cytosol

created [InstanceEdit:8848599] Orlic-Milacic, Marija, 2015年12月09日

dbId 8848596

displayName PTK6 binds PXN

edited

[InstanceEdit:8850988] Orlic-Milacic, Marija, 2016年01月04日

eventOf

[Pathway:R-HSA-8849471] PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases - Homo sapiens

followingEvent

[Reaction:R-HSA-8848606] PTK6 phosphorylates PXN - Homo sapiens

input

isChimeric false

isInDisease false

isInferred false

literatureReference

[LiteratureReference:8848601] Brk activates rac1 and promotes cell migration and invasion by phosphorylating paxillin

maxDepth 1

modified [InstanceEdit:10541496] Weiser, Joel, 2025年08月27日

name

PTK6 binds PXN

orthologousEvent

output

[Complex:R-HSA-8848597] p-Y342-PTK6:PXN [cytosol]

precedingEvent

[Reaction:R-HSA-8848005] ERBB2 promotes PTK6 autophosphorylation - Homo sapiens

releaseDate 2016年03月23日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

[InstanceEdit:8856649] Pires, Isabel M, 2016年02月07日

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-8848596

summation

[Summation:8848594] The SH2 and SH3 domains of PTK6 (BRK) interact with the N-te...

Referrals

(hasEvent)

[Pathway:R-HSA-8849471] PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases

(precedingEvent)

[Reaction:R-HSA-8848606] PTK6 phosphorylates PXN

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