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Schema
>
Reaction
>
Entries
TGM1 and involucrin bind the plasma membrane
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authored
[InstanceEdit:8863769] Jupe, Steve, 2016年03月10日
category
binding
compartment
[Compartment:70101] cytosol
[Compartment:876] plasma membrane
created
[InstanceEdit:6810925] Jupe, Steve, 2015年11月19日
dbId
6810899
displayName
TGM1 and involucrin bind the plasma membrane
edited
[InstanceEdit:8934545] Jupe, Steve, 2016年08月10日
eventOf
[Pathway:R-HSA-6809371] Formation of the cornified envelope - Homo sapiens
followingEvent
[BlackBoxEvent:R-HSA-6810894] Envoplakin, periplakin, involucrin, SPR binding mediated by TGM1 crosslinking - Homo sapiens
input
[OtherEntity:R-ALL-983438] Cell surface [plasma membrane]
[EntityWithAccessionedSequence:R-HSA-6810837] IVL [cytosol]
[EntityWithAccessionedSequence:R-HSA-6813756] TGM1 [cytosol]
isChimeric
false
isInDisease
false
isInferred
false
literatureReference
[LiteratureReference:6811548] The transglutaminase 1 enzyme is variably acylated by myristate and palmitate during differentiation in epidermal keratinocytes
[LiteratureReference:6811540] Involucrin cross-linking by transglutaminase 1. Binding to membranes directs residue specificity
[LiteratureReference:6811531] Bricks and mortar of the epidermal barrier
maxDepth
1
modified
[InstanceEdit:9830342] Matthews, Lisa, 2023年03月08日
name
TGM1 and involucrin bind the plasma membrane
output
[Complex:R-HSA-6814746] IVL:TGM1:Cell surface [plasma membrane]
releaseDate
2016年09月19日
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:8934809] Blumenberg, Miroslav, 2016年08月12日
schemaClass
Reaction
species
[Species:48887] Homo sapiens
stId
R-HSA-6810899
summation
[Summation:6810915] Transglutaminase-1 (TGM1) and involucrin (IVL) are expressed...
Referrals
(hasEvent)
[Pathway:R-HSA-6809371] Formation of the cornified envelope
(precedingEvent)
[BlackBoxEvent:R-HSA-6810894] Envoplakin, periplakin, involucrin, SPR binding mediated by TGM1 crosslinking
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