Reactome Pathway Database

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SFN dimerizes Show undefined attributes

authored

[InstanceEdit:6804719] Orlic-Milacic, Marija, 2015年10月14日

category binding

compartment

[Compartment:70101] cytosol

created [InstanceEdit:6803896] Orlic-Milacic, Marija, 2015年10月07日

dbId 6803890

displayName SFN dimerizes

edited

[InstanceEdit:6804719] Orlic-Milacic, Marija, 2015年10月14日

eventOf

[Pathway:R-HSA-6804114] TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest - Homo sapiens

followingEvent

input

2 × [EntityWithAccessionedSequence:R-HSA-1445105] SFN [cytosol]

isChimeric false

isInDisease false

isInferred false

literatureReference

[LiteratureReference:6803895] Characterization of 14-3-3sigma dimerization determinants: requirement of homodimerization for inhibition of cell proliferation

maxDepth 1

modified [InstanceEdit:11064438] Weiser, Joel, 2025年08月28日

name

SFN dimerizes

orthologousEvent

output

[Complex:R-HSA-6803886] SFN Dimer [cytosol]

precedingEvent

[BlackBoxEvent:R-HSA-6803871] TP53 stimulates SFN expression - Homo sapiens

releaseDate 2016年03月23日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-6803890

summation

[Summation:6803881] SFN functions as a homodimer (Verdoodt et al. 2006).

Referrals

(hasEvent)

[Pathway:R-HSA-6804114] TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest

(precedingEvent)

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