Reactome Pathway Database

Schema > BlackBoxEvent > Entries

26Sproteasome degrades K48polyUb-NIK Show undefined attributes

authored

[InstanceEdit:5668484] Garapati, Phani Vijay, 2015年01月26日

catalystActivity

[CatalystActivity:68824] endopeptidase activity of 26S proteasome [cytosol]

category omitted

compartment

[Compartment:70101] cytosol

created [InstanceEdit:5668515] Garapati, Phani Vijay, 2015年01月26日

dbId 5668520

displayName 26Sproteasome degrades K48polyUb-NIK

edited

[InstanceEdit:5668484] Garapati, Phani Vijay, 2015年01月26日

eventOf

[Pathway:R-HSA-5668541] TNFR2 non-canonical NF-kB pathway - Homo sapiens

input

[EntityWithAccessionedSequence:R-HSA-5668525] K48polyUb-NIK [cytosol]

isChimeric false

isInDisease false

isInferred false

literatureReference

maxDepth 1

modified [InstanceEdit:11033291] Weiser, Joel, 2025年08月28日

name

26Sproteasome degrades K48polyUb-NIK

orthologousEvent

precedingEvent

[BlackBoxEvent:R-HSA-5668534] cIAP1,2 ubiquitinates NIK in cIAP1,2:TRAF2::TRAF3:NIK - Homo sapiens

releaseDate 2015年06月17日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

[InstanceEdit:5692509] Ware, Carl F, Virgen-Slane, Richard, Rajput, Akhil, 2015年05月12日

schemaClass BlackBoxEvent

species

[Species:48887] Homo sapiens

stId R-HSA-5668520

summation

[Summation:5668521] Polyubiquitinated NIK is targeted for proteasomal degradatio...

Referrals

(hasEvent)

[Pathway:R-HSA-5668541] TNFR2 non-canonical NF-kB pathway

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