Reactome Pathway Database

Schema > EntityWithAccessionedSequence > Entries

MAP2K1(9-393) [cytosol] Show undefined attributes

compartment

[Compartment:70101] cytosol

created [InstanceEdit:5211335] D'Eustachio, Peter, 2013年12月09日

crossReference

[DatabaseIdentifier:11944952] Mondo:0005119

dbId 5211353

disease

[Disease:5205706] anthrax disease

displayName MAP2K1(9-393) [cytosol]

endCoordinate 393

inDisease true

literatureReference

[LiteratureReference:5211331] Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor
[LiteratureReference:5211349] Anthrax lethal factor cleaves the N-terminus of MAPKKs and induces tyrosine/threonine phosphorylation of MAPKs in cultured macrophages

maxDepth 1

modified [InstanceEdit:5211358] D'Eustachio, Peter, 2013年12月09日

name

MAP2K1(9-393)
MAP2K1 large LF fragment

producedByEvent

[Reaction:R-HSA-5211340] Anthrax lef cleaves target cell MAP2K1 (MEK1) - Homo sapiens

referenceEntity [ReferenceGeneProduct:uniprot:Q02750] UniProt:Q02750 MAP2K1

referenceType ReferenceGeneProduct

schemaClass EntityWithAccessionedSequence

species [Species:48887] Homo sapiens

stId R-HSA-5211353

startCoordinate 9

Referrals

(output)

[Reaction:R-HSA-5211340] Anthrax lef cleaves target cell MAP2K1 (MEK1)

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