Reactome | ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP

Schema > Reaction > Entries

ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP Show undefined attributes

Go to Details

authored

[InstanceEdit:749521] Dall'Olio, GM, 2009年11月10日

catalystActivity

[CatalystActivity:449313] N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity of ALG13:ALG14 [endoplasmic reticulum membrane]

category transition

compartment

[Compartment:12045] endoplasmic reticulum membrane

created [InstanceEdit:446206] Jassal, B, 2009年11月10日

dbId 446207

displayName ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP

edited

[InstanceEdit:446206] Jassal, B, 2009年11月10日

eventOf

[Pathway:R-HSA-446193] Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein - Homo sapiens

figure

[Figure:975569] /figures/2_GlcNAc2PPDol.png

followingEvent

[Reaction:R-HSA-446218] Addition of the first mannose to the N-glycan precursor by ALG1 - Homo sapiens

input

isChimeric false

isInDisease false

isInferred false

literatureReference

[LiteratureReference:449340] Alg14 recruits Alg13 to the cytoplasmic face of the endoplasmic reticulum to form a novel bipartite UDP-N-acetylglucosamine transferase required for the second step of N-linked glycosylation

maxDepth 1

modified [InstanceEdit:11064438] Weiser, Joel, 2025年08月28日

name

ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP
Addition of the second N-acetyl-glucosamine to the N-glycan precursor

orthologousEvent

output

precedingEvent

[Reaction:R-HSA-446191] Addition of N-acetyl-D-glucosamine to Dolichyl phosphate - Homo sapiens

releaseDate 2010年06月15日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

[InstanceEdit:749519] Gagneux, P, 2010年04月16日

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-446207

summation

[Summation:446220] A second N-acetylglucosamine is added to the N-glycan precur...

systematicName ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP

updateTrackers

[UpdateTracker:9790206] Update Tracker - [Reaction:446207] ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP - v34:[modifyText]

Referrals

(updatedInstance)

[UpdateTracker:9790206] Update Tracker - [Reaction:446207] ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP - v34:[modifyText]

(normalReaction)

[FailedReaction:R-HSA-5633241] Defective ALG14 does not transfer GlcNAc from UDP-GlcNAc to GlcNAcDOLP

(hasEvent)

[Pathway:R-HSA-446193] Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein

(precedingEvent)

[Reaction:R-HSA-446218] Addition of the first mannose to the N-glycan precursor by ALG1

Reactome Pathway Database

Reactome Pathway Database

ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP Show undefined attributes

Referrals

Cite Us!

Download As: