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Addition of a second glucose to the N-glycan precursor by ALG8 Show undefined attributes

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authored

[InstanceEdit:749521] Dall'Olio, GM, 2009年11月10日

catalystActivity

[CatalystActivity:449642] dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity of ALG8 [endoplasmic reticulum membrane]

category transition

compartment

[Compartment:17957] endoplasmic reticulum lumen

created [InstanceEdit:446206] Jassal, B, 2009年11月10日

dbId 446189

displayName Addition of a second glucose to the N-glycan precursor by ALG8

edited

[InstanceEdit:446206] Jassal, B, 2009年11月10日

eventOf

[Pathway:R-HSA-446193] Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein - Homo sapiens

figure

[Figure:975563] /figures/14_Glc2GlcNAc2Man9PPDol.png

followingEvent

[Reaction:R-HSA-446194] Addition of a third glucose to the N-glycan precursor by an ALG10 homologue - Homo sapiens

input

isChimeric false

isInDisease false

isInferred false

literatureReference

maxDepth 1

modified [InstanceEdit:11033291] Weiser, Joel, 2025年08月28日

name

Addition of a second glucose to the N-glycan precursor by ALG8

orthologousEvent

output

precedingEvent

[Reaction:R-HSA-446202] Addition of the first glucose to the N-glycan precursor by ALG6 - Homo sapiens

releaseDate 2010年06月15日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

[InstanceEdit:749519] Gagneux, P, 2010年04月16日

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-446189

summation

[Summation:449644] The second glucose (supplied from the donor dolichol-phospha...

updateTrackers

[UpdateTracker:9790209] Update Tracker - [Reaction:446189] Addition of a second glucose to the N-glycan precursor by ALG8 - v34:[add_removeInput]

Referrals

(updatedInstance)

[UpdateTracker:9790209] Update Tracker - [Reaction:446189] Addition of a second glucose to the N-glycan precursor by ALG8 - v34:[add_removeInput]

(normalReaction)

[FailedReaction:R-HSA-4724330] Defective ALG8 does not add glucose to the N-glycan precursor

(precedingEvent)

[Reaction:R-HSA-446194] Addition of a third glucose to the N-glycan precursor by an ALG10 homologue

(hasEvent)

[Pathway:R-HSA-446193] Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein

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