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GNE phosphorylates ManNAc to ManNAc-6-P Show undefined attributes

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authored

[InstanceEdit:4085031] Jassal, Bijay, 2013年08月01日

catalystActivity

[CatalystActivity:4085215] N-acylmannosamine kinase activity of GNE hexamer [cytosol]

category transition

compartment

[Compartment:70101] cytosol

created [InstanceEdit:4085031] Jassal, Bijay, 2013年08月01日

crossReference

[DatabaseIdentifier:12610567] Rhea:25254

dbId 4085028

displayName GNE phosphorylates ManNAc to ManNAc-6-P

edited

[InstanceEdit:4085031] Jassal, Bijay, 2013年08月01日

eventOf

[Pathway:R-HSA-4085001] Sialic acid metabolism - Homo sapiens

followingEvent

[Reaction:R-HSA-4084976] NANS converts ManNAc-6-P to Neu5Ac-9-P - Homo sapiens

input

isChimeric false

isInDisease false

isInferred false

literatureReference

maxDepth 1

modified [InstanceEdit:10680101] Weiser, Joel, 2025年08月27日

name

GNE phosphorylates ManNAc to ManNAc-6-P

orthologousEvent

output

precedingEvent

[Reaction:R-HSA-4085021] GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP - Homo sapiens

releaseDate 2014年03月12日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

[InstanceEdit:5225590] Medrano, Juan F, Wickramasinghe, Saumya, 2014年01月08日

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-4085028

summation

[Summation:4085199] UDP N acetylglucosamine 2 epimerase, N acetylmannosamine kin...

updateTrackers

Referrals

(updatedInstance)

(normalReaction)

[FailedReaction:R-HSA-4088322] Defective GNE does not phosphorylate ManNAc to ManNAc-6-P

(hasEvent)

[Pathway:R-HSA-4085001] Sialic acid metabolism

(precedingEvent)

[Reaction:R-HSA-4084976] NANS converts ManNAc-6-P to Neu5Ac-9-P

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