Reactome Pathway Database

Schema > Reaction > Entries

Plasmin proteolyzes IGF:IGFBP-3:ALS Show undefined attributes

catalystActivity

[CatalystActivity:158743] serine-type endopeptidase activity of Plasmin [extracellular region]

category transition

compartment

[Compartment:984] extracellular region

created [InstanceEdit:381505] May, B, 2008年11月19日 20:29:10

dbId 381461

displayName Plasmin proteolyzes IGF:IGFBP-3:ALS

edited

[InstanceEdit:381443] May, B, Gopinathrao, G, 2008年11月19日 20:02:07

eventOf

[Pathway:R-HSA-381426] Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) - Homo sapiens

input

[Complex:R-HSA-381536] IGF:IGFBP3:ALS [extracellular region]

isInDisease false

isInferred false

literatureReference

maxDepth 1

modified [InstanceEdit:10084857] Weiser, Joel, 2025年08月27日

name

Plasmin proteolyzes IGF:IGFBP-3:ALS

orthologousEvent

[Reaction:R-RNO-381461] Plasmin proteolyzes IGF:IGFBP-3:ALS - Rattus norvegicus

output

precedingEvent

[Reaction:R-HSA-381496] Formation of the IGF:IGFBP3:ALS complex - Homo sapiens

releaseDate 2008年12月17日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

[InstanceEdit:387470] D'Eustachio, P, Matthews, L, Gillespie, ME, 2008年12月02日 16:25:31

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-381461

summation

[Summation:381535] Plasmin cleaves IGFBP-3 in the IGF:IGFBP-3:ALS Complex betwe...

updateTrackers

[UpdateTracker:9790361] Update Tracker - [Reaction:381461] Plasmin proteolyzes IGF:IGFBP-3:ALS - v33:[add_removeLiteratureReference, modifyText]

Referrals

(updatedInstance)

[UpdateTracker:9790361] Update Tracker - [Reaction:381461] Plasmin proteolyzes IGF:IGFBP-3:ALS - v33:[add_removeLiteratureReference, modifyText]

(hasEvent)

[Pathway:R-HSA-381426] Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)

© 2025 Reactome

Cite Us!