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Entries
GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2
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authored
[InstanceEdit:3907318] D'Eustachio, P, 2013年07月19日
catalystActivity
[CatalystActivity:3781006] glycogen synthase activity, transferring glucose-1-phosphate of PPP1R3C:glycogen-GYG2:GYS2-a tetramer [cytosol]
category
transition
compartment
[Compartment:70101] cytosol
created
[InstanceEdit:3781010] D'Eustachio, P, 2013年06月27日
dbId
3780994
displayName
GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2
eventOf
[Pathway:R-HSA-3322077] Glycogen synthesis - Homo sapiens
followingEvent
[Reaction:R-HSA-3781021] EPM2A dimer binds PPP1R3C:phosphoglycogen-GYG2 complex - Homo sapiens
input
[Complex:R-HSA-3777104] PPP1R3C:glycogen-GYG2:GYS2-a tetramer [cytosol]
[SimpleEntity:R-ALL-29410] UDP-Glc [cytosol]
isChimeric
false
isInDisease
false
isInferred
false
literatureReference
[LiteratureReference:6805675] Glycogen phosphomonoester distribution in mouse models of the progressive myoclonic epilepsy, Lafora disease
[LiteratureReference:6805671] Muscle Glycogen Remodeling and Glycogen Phosphate Metabolism following Exhaustive Exercise of Wild Type and Laforin Knockout Mice
[LiteratureReference:6805680] Hyperphosphorylation of glucosyl C6 carbons and altered structure of glycogen in the neurodegenerative epilepsy Lafora disease
[LiteratureReference:3777087] Phosphate incorporation during glycogen synthesis and Lafora disease
[LiteratureReference:3777107] Malin decreases glycogen accumulation by promoting the degradation of protein targeting to glycogen (PTG)
maxDepth
1
modified
[InstanceEdit:11033291] Weiser, Joel, 2025年08月28日
name
GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2
negativePrecedingEvent
[NegativePrecedingEvent:9931470] Abundant Molecules: UTP + D-glucose 1-phosphate => pyrophosphate + UDP-glucose
orthologousEvent
[Reaction:R-SCE-3780994] GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2 - Saccharomyces cerevisiae
[Reaction:R-CEL-3780994] GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2 - Caenorhabditis elegans
[Reaction:R-DME-3780994] GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2 - Drosophila melanogaster
[Reaction:R-GGA-3780994] GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2 - Gallus gallus
[Reaction:R-SSC-3780994] GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2 - Sus scrofa
[Reaction:R-BTA-3780994] GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2 - Bos taurus
[Reaction:R-CFA-3780994] GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2 - Canis familiaris
output
[SimpleEntity:R-ALL-70106] H+ [cytosol]
[Complex:R-HSA-3777094] PPP1R3C:phosphoglycogen-GYG2:GYS2-a tetramer [cytosol]
[SimpleEntity:R-ALL-109402] UMP [cytosol]
precedingEvent
[Reaction:R-HSA-3780997] PPP1R3C binds to glycogen:GYG2:GYS2 - Homo sapiens
previousReviewStatus
[ReviewStatus:9821384] two stars
releaseDate
2013年06月11日
reviewStatus
[ReviewStatus:9821385] four stars
reviewed
[InstanceEdit:5333091] Pederson, Bart, 2014年02月18日
[InstanceEdit:4006079] Jassal, B, 2013年07月26日
schemaClass
Reaction
species
[Species:48887] Homo sapiens
stId
R-HSA-3780994
summation
[Summation:3781008] Glycogen synthase 2 (GYS2) catalyzes the incorporation of ph...
updateTrackers
[UpdateTracker:9783861] Update Tracker - [Reaction:3780994] GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2 - v55:[addLiteratureReference, modifyText]
[UpdateTracker:9939616] Update Tracker - [Reaction:3780994] GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2 - v92:[removeOutput]
Referrals
(updatedInstance)
[UpdateTracker:9783861] Update Tracker - [Reaction:3780994] GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2 - v55:[addLiteratureReference, modifyText]
[UpdateTracker:9939616] Update Tracker - [Reaction:3780994] GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2 - v92:[removeOutput]
(hasEvent)
[Pathway:R-HSA-3322077] Glycogen synthesis
(precedingEvent)
[Reaction:R-HSA-3781021] EPM2A dimer binds PPP1R3C:phosphoglycogen-GYG2 complex
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