Reactome | Malin decreases glycogen accumulation by promoting the degradation of protein targeting to glycogen (PTG)

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Malin decreases glycogen accumulation by promoting the degradation of protein targeting to glycogen (PTG) Show undefined attributes

author

[Person:179488] Worby, CA
[Person:3777100] Gentry, MS
[Person:111328] Dixon, JE

created [InstanceEdit:3777089] D'Eustachio, P, 2013年06月25日

dbId 3777107

displayName Malin decreases glycogen accumulation by promoting the degradation of protein targeting to glycogen (PTG)

journal J. Biol. Chem.

pages 4069-76

pubMedIdentifier 18070875

schemaClass LiteratureReference

title Malin decreases glycogen accumulation by promoting the degradation of protein targeting to glycogen (PTG)

url http://www.ncbi.nlm.nih.gov/pubmed/18070875

volume 283

year 2008

Referrals

(literatureReference)

[Complex:R-HSA-9037665] mutant EPM2A:PPP1R3C:phosphoglycogen-GYG1:GYS1-a tetramer [cytosol]
[Reaction:R-HSA-3781021] EPM2A dimer binds PPP1R3C:phosphoglycogen-GYG2 complex
[Reaction:R-HSA-3780994] GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2
[Reaction:R-HSA-3780997] PPP1R3C binds to glycogen:GYG2:GYS2
[BlackBoxEvent:R-HSA-3780995] NHLRC1 mediated ubiquitination of EPM2A (laforin) and PPP1RC3 (PTG) associated with glycogen-GYG2
[CatalystActivityReference:9931465] protein-macromolecule adaptor activity of PPP1R3C:phosphoglycogen-GYG2:GYS2-a tetramer [cytosol] Malin decreases glycogen accumulation by promoting the degradation of protein targeting to glycogen (PTG)
[Reaction:R-HSA-3781001] EPM2A dimer binds PPP1R3C:phosphoglycogen-GYG1 complex
[Reaction:R-HSA-3781023] PPP1R3C binds to glycogen:GYG1:GYS1
[BlackBoxEvent:R-HSA-3781009] NHLRC1 mediated ubiquitination of EPM2A and PPP1RC3 associated with glycogen-GYG1
[EntityWithAccessionedSequence:R-HSA-3781005] K48polyUb-PPP1R3C [cytosol]
[CatalystActivityReference:9931447] protein-macromolecule adaptor activity of PPP1R3C [cytosol] Malin decreases glycogen accumulation by promoting the degradation of protein targeting to glycogen (PTG)
[Complex:R-HSA-3777096] PPP1R3C:glycogen-GYG1:GYS1-a tetramer [cytosol]
[CatalystActivityReference:9931462] protein-macromolecule adaptor activity of PPP1R3C:phosphoglycogen-GYG1:GYS1-a tetramer [cytosol] Malin decreases glycogen accumulation by promoting the degradation of protein targeting to glycogen (PTG)
[Complex:R-HSA-3777093] PPP1R3C:phosphoglycogen-GYG1:GYS1-a tetramer [cytosol]
[Complex:R-HSA-3781000] EPM2A:PPP1R3C:glycogen-GYG1:GYS1-a tetramer [cytosol]
[Complex:R-HSA-3780999] EPM2A:PPP1R3C:phosphoglycogen-GYG1:GYS1-a tetramer [cytosol]

(author)

[Person:3777100] Gentry, MS
[Person:179488] Worby, CA
[Person:111328] Dixon, JE

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Malin decreases glycogen accumulation by promoting the degradation of protein targeting to glycogen (PTG) Show undefined attributes

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