Reactome Pathway Database
Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Reactome Pathway Database
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
Schema
>
DefinedSet
>
Entries
TGFBR2 MSI frameshift mutants [cytosol]
Show undefined attributes
Go to Details
compartment
[Compartment:70101] cytosol
consumedByEvent
[FailedReaction:R-HSA-3642203] Dimeric TGFB1 does not bind TGFBR2 MSI frameshift mutants - Homo sapiens
[FailedReaction:R-HSA-3642203] Dimeric TGFB1 does not bind TGFBR2 MSI frameshift mutants - Homo sapiens
created
[InstanceEdit:3642199] Orlic-Milacic, M, 2013年05月30日
crossReference
[DatabaseIdentifier:11944899] Mondo:0005575
[DatabaseIdentifier:11944892] Mondo:0004992
dbId
3642198
disease
[Disease:1500689] cancer
[Disease:1248674] large intestine cancer
displayName
TGFBR2 MSI frameshift mutants [cytosol]
hasMember
[EntityWithAccessionedSequence:R-HSA-3642173] TGFBR2 K128Afs*3 [cytosol] - Homo sapiens
[EntityWithAccessionedSequence:R-HSA-3642166] TGFBR2 K128Sfs*35 [cytosol] - Homo sapiens
inDisease
true
literatureReference
[LiteratureReference:3642171] Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability
[LiteratureReference:3642192] Demonstration that mutation of the type II transforming growth factor beta receptor inactivates its tumor suppressor activity in replication error-positive colon carcinoma cells
maxDepth
2
modified
[InstanceEdit:9634514] Orlic-Milacic, Marija, 2019年01月11日
name
TGFBR2 MSI frameshift mutants
TGFBR2 microsatellite instability frameshift mutants
TGFBR2 BAT-RII Mutants
schemaClass
DefinedSet
species
[Species:48887] Homo sapiens
stId
R-HSA-3642198
Referrals
(input)
[FailedReaction:R-HSA-3642203] Dimeric TGFB1 does not bind TGFBR2 MSI frameshift mutants
(diseaseEntity)
[EntityFunctionalStatus:3642202] loss_of_function of TGFBR2 MSI frameshift mutants [cytosol]
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
Download
Close
AltStyle
によって変換されたページ
(->オリジナル)
/
アドレス:
モード:
デフォルト
音声ブラウザ
ルビ付き
配色反転
文字拡大
モバイル