Reactome Pathway Database

Schema > Reaction > Entries

Cleavage of Satb1 Show undefined attributes

authored

[InstanceEdit:352235] Schulze-Osthoff, K, 2008年05月18日 10:00:05

catalystActivity

[CatalystActivity:352254] cysteine-type endopeptidase activity of active caspase-6 [nucleoplasm]

category transition

compartment

[Compartment:7660] nucleoplasm

created [InstanceEdit:352270] Matthews, L, 2008年06月02日 08:04:50

dbId 352268

displayName Cleavage of Satb1

edited

eventOf

[Pathway:R-HSA-111465] Apoptotic cleavage of cellular proteins - Homo sapiens

input

[EntityWithAccessionedSequence:R-HSA-201593] SATB1 [nucleoplasm]

isInDisease false

isInferred false

literatureReference

[LiteratureReference:352272] SATB1 cleavage by caspase 6 disrupts PDZ domain-mediated dimerization, causing detachment from chromatin early in T-cell apoptosis

maxDepth 1

modified [InstanceEdit:10680101] Weiser, Joel, 2025年08月27日

name

Cleavage of Satb1

orthologousEvent

output

precedingEvent

[BlackBoxEvent:R-HSA-9029690] Caspase-6 translocates to the nucleus - Homo sapiens

releaseDate 2008年06月30日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

[InstanceEdit:350641] Ranganathan, S, 2008年06月11日 19:13:33

revised

[InstanceEdit:350641] Ranganathan, S, 2008年06月11日 19:13:33

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-352268

summation

[Summation:352271] Cleaved Satb1 dissociates from chromatin and may function i...

Referrals

(hasEvent)

[Pathway:R-HSA-111465] Apoptotic cleavage of cellular proteins

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