Reactome Pathway Database

Schema > Reaction > Entries

PI3K phosphorylates PIP2 to PIP3 Show undefined attributes

authored

[InstanceEdit:2272794] Garapati, P V, 2012年05月25日

catalystActivity

[CatalystActivity:2424483] 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity of DAP12 Receptors:p-DAP12:p-6Y-SYK:PI3K [plasma membrane]

category transition

compartment

[Compartment:876] plasma membrane

created [InstanceEdit:2424489] Garapati, P V, 2012年07月23日

crossReference

[DatabaseIdentifier:12610421] Rhea:21292

dbId 2424480

displayName PI3K phosphorylates PIP2 to PIP3

edited

[InstanceEdit:2272794] Garapati, P V, 2012年05月25日

eventOf

[Pathway:R-HSA-2424491] DAP12 signaling - Homo sapiens

followingEvent

[Reaction:R-HSA-2424481] Recruitment of VAV and BTK to p-SLP-76 - Homo sapiens

input

isInDisease false

isInferred false

literatureReference

maxDepth 1

modified [InstanceEdit:10680101] Weiser, Joel, 2025年08月27日

name

PI3K phosphorylates PIP2 to PIP3

orthologousEvent

output

precedingEvent

[Reaction:R-HSA-2424482] p85 regulatory unit of PI3K binds p-6Y-SYK - Homo sapiens

releaseDate 2012年09月18日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

[InstanceEdit:2428957] Lanier, Lewis L, 2012年08月09日

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-2424480

summation

[Summation:2424321] Activated PI3K phosphorylates phosphatidylinositol (PI) 4-ph...

Referrals

(hasEvent)

[Pathway:R-HSA-2424491] DAP12 signaling

(precedingEvent)

[Reaction:R-HSA-2424481] Recruitment of VAV and BTK to p-SLP-76

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