Reactome Pathway Database

Schema > EntityWithAccessionedSequence > Entries

PIK3CA Q546L [cytosol] Show undefined attributes

candidateOf

[CandidateSet:R-HSA-2399587] PIK3CA helical domain mutants [cytosol] - Homo sapiens

compartment

[Compartment:70101] cytosol

created [InstanceEdit:2362369] Orlic-Milacic, M, 2012年06月27日

crossReference

dbId 2362375

disease

displayName PIK3CA Q546L [cytosol]

endCoordinate 1068

hasModifiedResidue

[ReplacedResidue:2362372] L-glutamine 546 replaced with L-leucine

inDisease true

literatureReference

[LiteratureReference:2399592] Mechanism of two classes of cancer mutations in the phosphoinositide 3-kinase catalytic subunit

maxDepth 1

modified [InstanceEdit:3662293] Orlic-Milacic, M, 2013年06月06日

name

PIK3CA Q546L
PIK3CA Gln546Leu

referenceEntity [ReferenceGeneProduct:uniprot:P42336] UniProt:P42336 PIK3CA

referenceType ReferenceGeneProduct

schemaClass EntityWithAccessionedSequence

species [Species:48887] Homo sapiens

stId R-HSA-2362375

startCoordinate 1

summation

[Summation:2399614] Based on structural and functional studies of PIK3CA Q546L m...

updateTrackers

[UpdateTracker:9888002] Update Tracker - [EntityWithAccessionedSequence:2362375] PIK3CA Q546L [cytosol] - v46:[modifyName]

Referrals

(updatedInstance)

[UpdateTracker:9888002] Update Tracker - [EntityWithAccessionedSequence:2362375] PIK3CA Q546L [cytosol] - v46:[modifyName]

(hasCandidate)

[CandidateSet:R-HSA-2399587] PIK3CA helical domain mutants [cytosol]

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