Reactome Pathway Database

Schema > EntityWithAccessionedSequence > Entries

PTEN R130Q [cytosol] Show undefined attributes

compartment

[Compartment:70101] cytosol

created [InstanceEdit:2317407] Orlic-Milacic, M, 2012年06月11日

crossReference

dbId 2317416

disease

displayName PTEN R130Q [cytosol]

endCoordinate 403

hasModifiedResidue

[ReplacedResidue:2317414] L-arginine 130 replaced with L-glutamine

inDisease true

literatureReference

[LiteratureReference:1889775] Functional evaluation of PTEN missense mutations using in vitro phosphoinositide phosphatase assay
[LiteratureReference:2317403] Molecular genetic defects in endometrial carcinomas: microsatellite instability, PTEN and beta-catenin (CTNNB1) genes mutations

maxDepth 1

memberOf

[CandidateSet:R-HSA-2317372] PTEN Phosphatase Domain Missense Mutants [cytosol] - Homo sapiens

modified [InstanceEdit:3662293] Orlic-Milacic, M, 2013年06月06日

name

PTEN R130Q
PTEN Arg130Gln

referenceEntity [ReferenceGeneProduct:uniprot:P60484] UniProt:P60484 PTEN

referenceType ReferenceGeneProduct

schemaClass EntityWithAccessionedSequence

species [Species:48887] Homo sapiens

stId R-HSA-2317416

startCoordinate 1

summation

[Summation:2317415] PTEN missense mutation that results in the substitution of a...

updateTrackers

[UpdateTracker:9888031] Update Tracker - [EntityWithAccessionedSequence:2317416] PTEN R130Q [cytosol] - v46:[modifyName]

Referrals

(updatedInstance)

[UpdateTracker:9888031] Update Tracker - [EntityWithAccessionedSequence:2317416] PTEN R130Q [cytosol] - v46:[modifyName]

(hasMember)

[CandidateSet:R-HSA-2317372] PTEN Phosphatase Domain Missense Mutants [cytosol]

© 2025 Reactome

Cite Us!