Reactome Pathway Database

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PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 Show undefined attributes

authored

[InstanceEdit:211006] Rudd, C.E., de Bono, B, Garapati, P V, 2008年01月24日 15:53:10

catalystActivity

[CatalystActivity:202288] 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity of PI3K bound to TRAT [plasma membrane]

category transition

compartment

created [InstanceEdit:202250] Garapati, P V, 2007年10月29日 14:08:25

crossReference

[DatabaseIdentifier:12610421] Rhea:21292

dbId 202365

displayName PI3K bound to TRAT1 phosphorylates PIP2 to PIP3

eventOf

[Pathway:R-HSA-202424] Downstream TCR signaling - Homo sapiens

figure

[Figure:179450] /figures/pi3k_converts_pip2_2_pip3.jpg

followingEvent

input

isInDisease false

isInferred false

literatureReference

[LiteratureReference:202402] The role of PI3K in immune cells

maxDepth 1

modified [InstanceEdit:10680101] Weiser, Joel, 2025年08月27日

name

PI3K bound to TRAT1 phosphorylates PIP2 to PIP3

orthologousEvent

output

precedingEvent

[Reaction:R-HSA-202203] Recruitment of PI3K to plasma membrane - Homo sapiens

releaseDate 2008年03月12日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

[InstanceEdit:214481] Trowsdale, J, 2008年02月26日 12:02:59

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-202365

summation

[Summation:202398] PI3K enzyme bound to adaptor protein TRIM, uses phosphatidyl...

Referrals

(hasEvent)

[Pathway:R-HSA-202424] Downstream TCR signaling

(precedingEvent)

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