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Schema > Reaction > Entries

AKT1 phosphorylates eNOS Show undefined attributes

authored

[InstanceEdit:202104] Hemish, J, 2007年10月19日 18:00:42

catalystActivity

[CatalystActivity:9911152] protein serine/threonine kinase activity of eNOS:CaM:HSP90:p-AKT1 [plasma membrane]

catalystActivityReference [CatalystActivityReference:9911161] protein serine/threonine kinase activity of eNOS:CaM:HSP90:p-AKT1 [plasma membrane] Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation

category transition

compartment

created [InstanceEdit:202104] Hemish, J, 2007年10月19日 18:00:42

crossReference

[DatabaseIdentifier:9857128] RHEA:17990

dbId 202111

displayName AKT1 phosphorylates eNOS

eventOf

followingEvent

[Reaction:R-HSA-1497784] The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle - Homo sapiens

input

isInDisease false

isInferred false

literatureReference

maxDepth 1

modified [InstanceEdit:11064438] Weiser, Joel, 2025年08月28日

name

AKT1 phosphorylates eNOS
ATP + L-seryl-(protein) => ADP + H(+) + O-phospho-L-seryl-(protein)

orthologousEvent

output

precedingEvent

[Reaction:R-HSA-202137] AKT1 binds eNOS complex via HSP90 - Homo sapiens

previousReviewStatus [ReviewStatus:9821385] four stars

releaseDate 2008年03月12日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-202111

summation

[Summation:202115] HSP90 serves as a scaffold to promote productive interaction...

updateTrackers

Referrals

(updatedInstance)

(hasEvent)

(precedingEvent)

[Reaction:R-HSA-1497784] The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle

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