Reactome | Removal of fibrillar collagen C-propeptides

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Removal of fibrillar collagen C-propeptides Show undefined attributes

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authored

[InstanceEdit:913966] Jupe, S, 2010年07月20日

catalystActivity

[CatalystActivity:2002398] metalloendopeptidase activity of Procollagen C-proteinases [extracellular region]

category transition

compartment

[Compartment:984] extracellular region

created [InstanceEdit:2002388] Jupe, S, 2011年11月21日

dbId 2002440

displayName Removal of fibrillar collagen C-propeptides

edited

[InstanceEdit:2247551] Jupe, S, 2012年05月14日

eventOf

[Pathway:R-HSA-1650814] Collagen biosynthesis and modifying enzymes - Homo sapiens

followingEvent

[Polymerisation:R-HSA-1474266] Formation of collagen fibrils - Homo sapiens

input

[DefinedSet:R-HSA-2268931] Fibrillar procollagens -N [extracellular region]

isChimeric false

isInDisease false

isInferred false

literatureReference

maxDepth 1

modified [InstanceEdit:10867632] Weiser, Joel, 2025年08月27日

name

Removal of fibrillar collagen C-propeptides

orthologousEvent

output

[DefinedSet:R-HSA-2060921] Tropocollagens [extracellular region]

precedingEvent

[Reaction:R-HSA-2002428] Removal of fibrillar collagen N-propeptides - Homo sapiens

regulatedBy

[PositiveRegulation:R-HSA-2267335] Positive regulation by 'PCOLCEs [extracellular region]'

regulationReference

[RegulationReference:9641790] Positive regulation by 'PCOLCEs [extracellular region]' PCOLCE2 encodes a functional procollagen C-proteinase enhancer (PCPE2) that is a collagen-binding protein differing in distribution of expression and post-translational modification from the previously described PCPE1

releaseDate 2012年06月12日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

[InstanceEdit:2267224] Canty-Laird, EG, 2012年05月24日

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-2002440

summation

[Summation:2002400] Fibrillar collagen is synthesized in the ER as procollagen w...

Referrals

(hasEvent)

[Pathway:R-HSA-1650814] Collagen biosynthesis and modifying enzymes

(precedingEvent)

[Polymerisation:R-HSA-1474266] Formation of collagen fibrils

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Reactome Pathway Database

Removal of fibrillar collagen C-propeptides Show undefined attributes

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