Reactome Pathway Database

Schema > Complex > Entries

p-T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] Show undefined attributes

catalystActivities

[CatalystActivity:196225] protein serine/threonine kinase activity of p-T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol]

compartment

[Compartment:70101] cytosol

consumedByEvent

[Reaction:R-HSA-195283] Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 - Homo sapiens

created [InstanceEdit:195272] Matthews, L, 2007年04月03日 12:38:03

dbId 195313

displayName p-T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol]

hasComponent

inDisease false

inferredTo

maxDepth 5

modified [InstanceEdit:8943895] Rothfels, Karen, 2016年10月31日

name

p-T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex

producedByEvent

[Reaction:R-HSA-195287] Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 - Homo sapiens

schemaClass Complex

species

[Species:48887] Homo sapiens

stId R-HSA-195313

updateTrackers

Referrals

(updatedInstance)

(normalEntity)

[EntityFunctionalStatus:4839620] loss_of_function of pT41,S45-CTNNB1 S37 mutants:Axin:GSK3:CK1alpha:APC:PP2A:AMER1 complex [cytosol]

(output)

[Reaction:R-HSA-195287] Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3

(input)

[Reaction:R-HSA-195283] Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3

(physicalEntity)

[CatalystActivity:196225] protein serine/threonine kinase activity of p-T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol]

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