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Pro-EGF is cleaved to form mature EGF Show undefined attributes

authored

[InstanceEdit:188408] Castagnoli, L, 2006年10月10日 13:09:34

catalystActivity

[CatalystActivity:179871] metalloendopeptidase activity of ADAM:Zn2+ [plasma membrane]

category transition

compartment

created [InstanceEdit:177921] Jassal, Bijay, 2006年04月11日

dbId 177946

displayName Pro-EGF is cleaved to form mature EGF

eventOf

[Pathway:R-HSA-177929] Signaling by EGFR - Homo sapiens

followingEvent

[Reaction:R-HSA-177942] EGFR binds EGF ligand - Homo sapiens

inferredFrom

[Reaction:R-MMU-179883] Mouse pro-EGF is cleaved by ADAM sheddases - Mus musculus

input

[EntityWithAccessionedSequence:R-HSA-179888] Pro-EGF [plasma membrane]

isInDisease false

isInferred true

maxDepth 1

modified [InstanceEdit:9830342] Matthews, Lisa, 2023年03月08日

name

Pro-EGF is cleaved to form mature EGF

output

[EntityWithAccessionedSequence:R-HSA-179863] EGF [extracellular region]

releaseDate 2007年02月20日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

[InstanceEdit:193358] Muthuswamy, S, 2007年02月16日 20:08:05

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-177946

summation

[Summation:179818] Ligands of the epidermal growth factor receptor (EGFR) are ...

updateTrackers

[UpdateTracker:9792081] Update Tracker - [Reaction:177946] Pro-EGF is cleaved to form mature EGF - v24:[modifyText]

Referrals

(updatedInstance)

[UpdateTracker:9792081] Update Tracker - [Reaction:177946] Pro-EGF is cleaved to form mature EGF - v24:[modifyText]

(hasEvent)

[Pathway:R-HSA-177929] Signaling by EGFR

(precedingEvent)

[Reaction:R-HSA-177942] EGFR binds EGF ligand

(inferredTo)

[Reaction:R-MMU-179883] Mouse pro-EGF is cleaved by ADAM sheddases

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