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SHC1 phosphorylation by phosphorylated EGFR Show undefined attributes

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authored

[InstanceEdit:188408] Castagnoli, L, 2006年10月10日 13:09:34

catalystActivity

[CatalystActivity:9624433] transmembrane receptor protein tyrosine kinase activity of EGF-like ligands:p-6Y EGFR:SHC1 [plasma membrane]

category transition

compartment

created [InstanceEdit:177921] Jassal, Bijay, 2006年04月11日

dbId 177933

displayName SHC1 phosphorylation by phosphorylated EGFR

edited

[InstanceEdit:1529121] Orlic-Milacic, Marija, 2011年08月25日

eventOf

[Pathway:R-HSA-180336] SHC1 events in EGFR signaling - Homo sapiens

figure

[Figure:179445] /figures/egfr_phos_of_shc_.jpg

followingEvent

[Reaction:R-HSA-177936] GRB2:SOS1 binds to phosphorylated SHC1 in complex with EGFR - Homo sapiens

input

isInDisease false

isInferred false

literatureReference

maxDepth 1

modified [InstanceEdit:10778922] Weiser, Joel, 2025年08月27日

name

SHC1 phosphorylation by phosphorylated EGFR

orthologousEvent

output

precedingEvent

[Reaction:R-HSA-177925] SHC1 binds to the phosphorylated EGF receptor:ligand complex - Homo sapiens

releaseDate 2008年03月12日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

[InstanceEdit:212476] Heldin, CH, 2008年02月12日 09:44:02

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-177933

summation

[Summation:188540] Once bound to EGFR, SHC1 is phosphorylated on two tyrosines ...

updateTrackers

Referrals

(updatedInstance)

(normalReaction)

(hasEvent)

[Pathway:R-HSA-180336] SHC1 events in EGFR signaling

(precedingEvent)

[Reaction:R-HSA-177936] GRB2:SOS1 binds to phosphorylated SHC1 in complex with EGFR

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