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Schema
>
Reaction
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Entries
D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate
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catalystActivity
[CatalystActivity:71333] transaldolase activity of TALDO1 dimer [cytosol]
catalystActivityReference
[CatalystActivityReference:9643115] sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity of TALDO1 dimer [cytosol] The three-dimensional structure of human transaldolase
category
transition
compartment
[Compartment:70101] cytosol
created
[InstanceEdit:163728] Gopinathrao, G, 2005年05月06日 17:09:17
crossReference
[DatabaseIdentifier:9934060] RHEA:17055
dbId
163764
displayName
D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate
eventOf
[Pathway:R-HSA-163754] Insulin effects increased synthesis of Xylulose-5-Phosphate - Homo sapiens
[Pathway:R-HSA-71336] Pentose phosphate pathway - Homo sapiens
followingEvent
[Reaction:R-HSA-163741] D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate - Homo sapiens
input
[SimpleEntity:R-ALL-29878] E4P [cytosol]
[SimpleEntity:R-ALL-29512] Fru(6)P [cytosol]
isInDisease
false
isInferred
false
literatureReference
[LiteratureReference:467367] Cloning and expression of the human gene for transaldolase. A novel highly repetitive element constitutes an integral part of the coding sequence
[LiteratureReference:5659967] The three-dimensional structure of human transaldolase
[LiteratureReference:71326] Transaldolase deficiency: liver cirrhosis associated with a new inborn error in the pentose phosphate pathway.
maxDepth
1
modified
[InstanceEdit:11033291] Weiser, Joel, 2025年08月28日
name
D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate
TALDO1 transforms Fru(6)P and E4P to sedoheptulose 7-phosphate and GA3P
orthologousEvent
[Reaction:R-SCE-163764] D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate - Saccharomyces cerevisiae
[Reaction:R-SPO-163764] D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate - Schizosaccharomyces pombe
[Reaction:R-DDI-163764] D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate - Dictyostelium discoideum
[Reaction:R-CEL-163764] D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate - Caenorhabditis elegans
[Reaction:R-DME-163764] D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate - Drosophila melanogaster
[Reaction:R-GGA-163764] D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate - Gallus gallus
[Reaction:R-XTR-163764] D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate - Xenopus tropicalis
[Reaction:R-DRE-163764] D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate - Danio rerio
[Reaction:R-SSC-163764] D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate - Sus scrofa
[Reaction:R-BTA-163764] D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate - Bos taurus
[Reaction:R-CFA-163764] D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate - Canis familiaris
[Reaction:R-RNO-163764] D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate - Rattus norvegicus
[Reaction:R-MMU-163764] D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate - Mus musculus
output
[SimpleEntity:R-ALL-29578] GA3P [cytosol]
[SimpleEntity:R-ALL-29882] SH7P [cytosol]
precedingEvent
[Reaction:R-HSA-70471] GPI dimer isomerizes G6P - Homo sapiens
releaseDate
2005年09月26日
reverseReaction
[Reaction:R-HSA-71334] sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate
reviewStatus
[ReviewStatus:9821382] five stars
revised
[InstanceEdit:469644] D'Eustachio, P, 2010年01月24日
schemaClass
Reaction
species
[Species:48887] Homo sapiens
stId
R-HSA-163764
summation
[Summation:178631] Dimeric cytosolic transaldolase (TALDO1) catalyzes the rever...
updateTrackers
[UpdateTracker:9864120] Update Tracker - [Reaction:163764] D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate - v88:[modifyText]
[UpdateTracker:9790959] Update Tracker - [Reaction:163764] D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate - v32:[addLiteratureReference, modifyText]
[UpdateTracker:9784967] Update Tracker - [Reaction:163764] D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate - v52:[addLiteratureReference, modifyText]
[UpdateTracker:9792270] Update Tracker - [Reaction:163764] D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate - v22:[addLiteratureReference]
Referrals
(updatedInstance)
[UpdateTracker:9864120] Update Tracker - [Reaction:163764] D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate - v88:[modifyText]
[UpdateTracker:9790959] Update Tracker - [Reaction:163764] D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate - v32:[addLiteratureReference, modifyText]
[UpdateTracker:9784967] Update Tracker - [Reaction:163764] D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate - v52:[addLiteratureReference, modifyText]
[UpdateTracker:9792270] Update Tracker - [Reaction:163764] D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate - v22:[addLiteratureReference]
(hasEvent)
[Pathway:R-HSA-163754] Insulin effects increased synthesis of Xylulose-5-Phosphate
[Pathway:R-HSA-71336] Pentose phosphate pathway
(normalReaction)
[FailedReaction:R-HSA-5659998] Defective TALDO1 does not transform Fru(6)P, E4P to SH7P, GA3P
(precedingEvent)
[Reaction:R-HSA-163741] D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate
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