Reactome Pathway Database

Schema > Reaction > Entries

Initial activation of proMMP3 Show undefined attributes

authored

[InstanceEdit:1592294] Jupe, S, 2011年09月09日

catalystActivity

[CatalystActivity:1604720] serine-type endopeptidase activity of proMMP3 initial activators [extracellular region]

category transition

compartment

[Compartment:984] extracellular region

created [InstanceEdit:1592294] Jupe, S, 2011年09月09日

dbId 1592371

displayName Initial activation of proMMP3

edited

[InstanceEdit:2129374] Jupe, S, 2012年02月21日

eventOf

[Pathway:R-HSA-1592389] Activation of Matrix Metalloproteinases - Homo sapiens

followingEvent

[Reaction:R-HSA-1604731] Autocatalytic activation of MMP3 - Homo sapiens

input

[EntityWithAccessionedSequence:R-HSA-1604707] MMP3(18-477) [extracellular region]

isChimeric false

isInDisease false

isInferred false

literatureReference

maxDepth 1

modified [InstanceEdit:10867632] Weiser, Joel, 2025年08月27日

name

Initial activation of proMMP3

orthologousEvent

output

releaseDate 2012年03月13日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-1592371

summation

[Summation:1592289] proMMP3 is activated in a similar manner to pro MMP1 but by ...

updateTrackers

[UpdateTracker:9788597] Update Tracker - [Reaction:1592371] Initial activation of proMMP3 - v41:[modifyText]

Referrals

(updatedInstance)

[UpdateTracker:9788597] Update Tracker - [Reaction:1592371] Initial activation of proMMP3 - v41:[modifyText]

(hasEvent)

[Pathway:R-HSA-1592389] Activation of Matrix Metalloproteinases

(precedingEvent)

[Reaction:R-HSA-1604731] Autocatalytic activation of MMP3

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