Reactome Pathway Database

Schema > Reaction > Entries

Full activation of MMP1 Show undefined attributes

authored

[InstanceEdit:1592294] Jupe, S, 2011年09月09日

catalystActivity

[CatalystActivity:1604375] serine-type endopeptidase activity of MMP2,3,7,10,11 [extracellular region]

category transition

compartment

[Compartment:984] extracellular region

created [InstanceEdit:1592294] Jupe, S, 2011年09月09日

dbId 1592297

displayName Full activation of MMP1

edited

[InstanceEdit:2129374] Jupe, S, 2012年02月21日

eventOf

[Pathway:R-HSA-1592389] Activation of Matrix Metalloproteinases - Homo sapiens

followingEvent

[Reaction:R-HSA-1604359] Initial activation of proMMP2 by MMP1, 7 - Homo sapiens

input

[EntityWithAccessionedSequence:R-HSA-1604355] MMP1(84-469) [extracellular region]

isChimeric false

isInDisease false

isInferred false

literatureReference

maxDepth 1

modified [InstanceEdit:10867632] Weiser, Joel, 2025年08月27日

name

Full activation of MMP1

orthologousEvent

output

[EntityWithAccessionedSequence:R-HSA-375064] MMP1(100-469) [extracellular region]

precedingEvent

[Reaction:R-HSA-1602473] Autocatalytic activation of MMP1 - Homo sapiens

releaseDate 2012年03月13日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-1592297

summation

[Summation:1592348] The 42 kDa intermediate form of MMP1 is fully activated by c...

Referrals

(hasEvent)

[Pathway:R-HSA-1592389] Activation of Matrix Metalloproteinases

(precedingEvent)

[Reaction:R-HSA-1604359] Initial activation of proMMP2 by MMP1, 7

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