Reactome Pathway Database

Schema > EntityWithAccessionedSequence > Entries

PIK3CA Q546K [cytosol] Show undefined attributes

compartment

[Compartment:70101] cytosol

created [InstanceEdit:1500696] Orlic-Milacic, Marija, 2011年08月19日

crossReference

dbId 1500705

disease

displayName PIK3CA Q546K [cytosol]

endCoordinate 1068

hasModifiedResidue

[ReplacedResidue:1500698] L-glutamine 546 replaced with L-lysine

inDisease true

literatureReference

[LiteratureReference:1500710] High frequency of mutations of the PIK3CA gene in human cancers
[LiteratureReference:2399592] Mechanism of two classes of cancer mutations in the phosphoinositide 3-kinase catalytic subunit

maxDepth 1

memberOf

[CandidateSet:R-HSA-2399587] PIK3CA helical domain mutants [cytosol] - Homo sapiens

modified [InstanceEdit:3662293] Orlic-Milacic, M, 2013年06月06日

name

PIK3CA Q546K
PIK3CA Gln546Lys

referenceEntity [ReferenceGeneProduct:uniprot:P42336] UniProt:P42336 PIK3CA

referenceType ReferenceGeneProduct

schemaClass EntityWithAccessionedSequence

species [Species:48887] Homo sapiens

stId R-HSA-1500705

startCoordinate 1

summation

[Summation:2399600] Substitution of glutamine residue at position 546 of PIK3CA ...

updateTrackers

[UpdateTracker:9887742] Update Tracker - [EntityWithAccessionedSequence:1500705] PIK3CA Q546K [cytosol] - v46:[modifyName]

Referrals

(updatedInstance)

[UpdateTracker:9887742] Update Tracker - [EntityWithAccessionedSequence:1500705] PIK3CA Q546K [cytosol] - v46:[modifyName]

(hasMember)

[CandidateSet:R-HSA-2399587] PIK3CA helical domain mutants [cytosol]

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