Reactome Pathway Database

Schema > Reaction > Entries

RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers Show undefined attributes

category binding

compartment

[Compartment:876] plasma membrane

created [InstanceEdit:10680101] Weiser, Joel, 2025年08月27日

dbId 10743085

displayName RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers

eventOf

[Pathway:R-GGA-5673000] RAF activation - Gallus gallus

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

inferredFrom

[Reaction:R-HSA-5672966] RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers

output

[Complex:R-GGA-5672733] p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane]

precedingEvent

[Reaction:R-GGA-5672950] "Activator" RAF:YWHAB dimer binds RAS:GTP - Gallus gallus

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:49591] Gallus gallus

stId R-GGA-5672966

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-GGA-5673000] RAF activation

(precedingEvent)

(inferredTo)

[Reaction:R-HSA-5672966] RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers

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