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Schema
>
Reaction
>
Entries
Released NFkB complex migrates to the nucleus and turns on transcription
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authored
[InstanceEdit:434153] Shamovsky, V, 2009年08月26日
category
transition
compartment
[Compartment:70101] cytosol
[Compartment:7660] nucleoplasm
[Compartment:13231] nuclear envelope
created
[InstanceEdit:434122] Shamovsky, V, 2009年08月26日
dbId
433823
displayName
Released NFkB complex migrates to the nucleus and turns on transcription
edited
[InstanceEdit:668815] Shamovsky, V, 2010年05月04日
eventOf
[Pathway:R-GGA-434001] TAK1 activates NFkB by phosphorylation and activation of IKKs complex - Gallus gallus
[Pathway:R-GGA-434131] NFkB activation mediated by RIP1 complexed with activated TLR3 - Gallus gallus
inferredFrom
[Reaction:R-HSA-168166] NF-kappa-B complex is transported from cytosol to nucleus - Homo sapiens
input
[Complex:R-GGA-434125] NFkB complex(p50/p65) [cytosol]
isInDisease
false
isInferred
true
literatureReference
[LiteratureReference:202539] Signaling to NF-kappaB
[LiteratureReference:202538] The two NF-kappaB activation pathways and their role in innate and adaptive immunity
[LiteratureReference:202509] Ubiquitin signalling in the NF-kappaB pathway
maxDepth
1
modified
[InstanceEdit:9830342] Matthews, Lisa, 2023年03月08日
name
Released NFkB complex migrates to the nucleus and turns on transcription
output
[Complex:R-GGA-433908] NFkB complex(p50/p65) [nucleoplasm]
precedingEvent
[Reaction:R-GGA-433986] activated IKKs phosphorylates IkB alpha causing the NFkB complex to dissociate from the phospho-IkB - Gallus gallus
releaseDate
2010年12月14日
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:789693] D'Eustachio, P, 2010年05月23日
schemaClass
Reaction
species
[Species:49591] Gallus gallus
stId
R-GGA-433823
summation
[Summation:433791] NFkB is a family of transcription factors that play pivotal ...
[Summation:571159] Chicken NFkB p105 (precursor of p50) subunit and NFkB p65 su...
updateTrackers
[UpdateTracker:9774780] Update Tracker - [Reaction:433823] Released NFkB complex migrates to the nucleus and turns on transcription - v81:[modifyText]
[UpdateTracker:9788185] Update Tracker - [Reaction:433823] Released NFkB complex migrates to the nucleus and turns on transcription - v43:[modifyText]
Referrals
(updatedInstance)
[UpdateTracker:9774780] Update Tracker - [Reaction:433823] Released NFkB complex migrates to the nucleus and turns on transcription - v81:[modifyText]
[UpdateTracker:9788185] Update Tracker - [Reaction:433823] Released NFkB complex migrates to the nucleus and turns on transcription - v43:[modifyText]
(hasEvent)
[Pathway:R-GGA-434131] NFkB activation mediated by RIP1 complexed with activated TLR3
[Pathway:R-GGA-434001] TAK1 activates NFkB by phosphorylation and activation of IKKs complex
(inferredTo)
[Reaction:R-HSA-168166] NF-kappa-B complex is transported from cytosol to nucleus
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