Reactome Pathway Database

Schema > Reaction > Entries

PDGFRs bind type I TKI Show undefined attributes

category binding

compartment

created [InstanceEdit:10541496] Weiser, Joel, 2025年08月27日

dbId 10595193

displayName PDGFRs bind type I TKI

eventOf

[Pathway:R-DRE-186797] Signaling by PDGF - Danio rerio

evidenceType [EvidenceType:9965817] inferred by electronic annotation

inferredFrom

[Reaction:R-HSA-9674093] PDGFRs bind type I TKI - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

PDGFRs bind type I TKI

output

[Complex:R-DRE-9674082] PDGFR:type I PDGFR-binding TKIs [plasma membrane]

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:68323] Danio rerio

stId R-DRE-9674093

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-DRE-186797] Signaling by PDGF

(inferredTo)

[Reaction:R-HSA-9674093] PDGFRs bind type I TKI

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