Reactome Pathway Database

Schema > Reaction > Entries

GSS:Mg2+ dimer synthesizes GSH Show undefined attributes

catalystActivity

[CatalystActivity:10548582] glutathione synthase activity of GSS:Mg2+ dimer [cytosol]

category transition

compartment

[Compartment:70101] cytosol

created [InstanceEdit:10541496] Weiser, Joel, 2025年08月27日

dbId 10548584

displayName GSS:Mg2+ dimer synthesizes GSH

eventOf

[Pathway:R-DRE-174403] Glutathione synthesis and recycling - Danio rerio

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

inferredFrom

[Reaction:R-HSA-174394] GSS:Mg2+ dimer synthesizes GSH - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

GSS:Mg2+ dimer synthesizes GSH
gamma-glutamylcysteine combines with glycine to form glutathione

output

precedingEvent

[Reaction:R-DRE-1247910] CNDP2:2Mn2+ dimer hydrolyses CysGly - Danio rerio

regulatedBy

[NegativeRegulation:R-HSA-1260991] Negative regulation by 'GSH [cytosol]'

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:68323] Danio rerio

stId R-DRE-174394

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(precedingEvent)

(hasEvent)

[Pathway:R-DRE-174403] Glutathione synthesis and recycling

(inferredTo)

[Reaction:R-HSA-174394] GSS:Mg2+ dimer synthesizes GSH

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