Reactome Pathway Database

Schema > Reaction > Entries

DLAT trimer transfers acetyl to CoA Show undefined attributes

catalystActivity

[CatalystActivity:10303614] dihydrolipoyllysine-residue acetyltransferase activity of PDH complex [mitochondrial matrix]

category transition

compartment

created [InstanceEdit:10201029] Weiser, Joel, 2025年08月27日

dbId 10303616

displayName DLAT trimer transfers acetyl to CoA

eventOf

[Pathway:R-CFA-9861559] PDH complex synthesizes acetyl-CoA from PYR - Canis familiaris

evidenceType [EvidenceType:9965817] inferred by electronic annotation

followingEvent

inferredFrom

[Reaction:R-HSA-9861667] DLAT trimer transfers acetyl to CoA - Homo sapiens

input

isInDisease false

isInferred true

maxDepth 1

name

DLAT trimer transfers acetyl to CoA

output

precedingEvent

regulatedBy

[NegativeRegulation:10303617] Negative regulation by 'DLAT [mitochondrial matrix]'

releaseDate 2025年09月18日

schemaClass Reaction

species

[Species:49646] Canis familiaris

stId R-CFA-9861667

summation

[Summation:9965816] This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)

[Pathway:R-CFA-9861559] PDH complex synthesizes acetyl-CoA from PYR

(precedingEvent)

(inferredTo)

[Reaction:R-HSA-9861667] DLAT trimer transfers acetyl to CoA

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